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Review
. 2022 Apr 12;12(8):997.
doi: 10.3390/ani12080997.

Nutritional Modulation, Gut, and Omics Crosstalk in Ruminants

Mohamed Abdelrahman  1   2 , Wei Wang  1 , Aftab Shaukat  1 , Muhammad Fakhar-E-Alam Kulyar  3 , Haimiao Lv  1 , Adili Abulaiti  1 , Zhiqiu Yao  1 , Muhammad Jamil Ahmad  1 , Aixin Liang  1   4 , Liguo Yang  1   4
Affiliations
Review

Nutritional Modulation, Gut, and Omics Crosstalk in Ruminants

Mohamed Abdelrahman et al. Animals (Basel). .

Abstract

Ruminant nutrition has significantly revolutionized a new and prodigious molecular approach in livestock sciences over the last decade. Wide-spectrum advances in DNA and RNA technologies and analysis have produced a wealth of data that have shifted the research threshold scheme to a more affluent level. Recently, the published literature has pointed out the nutrient roles in different cellular genomic alterations among different ruminant species, besides the interactions with other factors, such as age, type, and breed. Additionally, it has addressed rumen microbes within the gut health and productivity context, which has made interpreting homogenous evidence more complicated. As a more systematic approach, nutrigenomics can identify how genomics interacts with nutrition and other variables linked to animal performance. Such findings should contribute to crystallizing powerful interpretations correlating feeding management with ruminant production and health through genomics. This review will present a road-mapping discussion of promising trends in ruminant nutrigenomics as a reference for phenotype expression through multi-level omics changes.

Keywords: feedomics; gene expression; nutrigenomics; nutrition; ruminant; transcriptome.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Potential of different dietary components and characteristics of molecular changes in a ruminant model.
Figure 2
Figure 2
Nutrition–gene interaction pathway in ruminants.
Figure 3
Figure 3
Animal factors that can change the feedomics imprint.
See this image and copyright information in PMC

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