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Review
. 2022 Apr 14;58(4):541.
doi: 10.3390/medicina58040541.

Cardiac Biomarkers in Patients with Acute Pulmonary Embolism

Luc Janisset  1   2 , Maxime Castan  1 , Géraldine Poenou  3 , Raphael Lachand  4 , Patrick Mismetti  2   3 , Alain Viallon  1 , Laurent Bertoletti  2   3   5
Affiliations
Review

Cardiac Biomarkers in Patients with Acute Pulmonary Embolism

Luc Janisset et al. Medicina (Kaunas). .

Abstract

Pulmonary embolism is a frequent and potentially fatal disease. The major challenge of initial management lies in prognostic stratification. Since 2014, the European recommendations on the diagnosis and management of acute pulmonary embolism are based on assessing the risk stratification regarding hemodynamic status first, then on a combined risk assessment model using a clinical score, an imaging evaluation of right heart size and the concentration of a serum cardiac biomarker. Usual biomarkers cover cardiac ischemia (troponin and derivates) and dilatation (BNP and derivates). The aim of this review is to offer a practical update on the role of the Troponins and BNPs families of biomarkers and the prognosis of pulmonary embolism, and furthermore, to provide a brief overview of their place in current management.

Keywords: NT-proBNP; cardiac biomarker; pulmonary embolism; sPESI; troponin.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The new potential role of the cardiac biomarkers in acute PE.
See this image and copyright information in PMC

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