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Review
. 2022 Apr 11;9(4):538.
doi: 10.3390/children9040538.

Critically Ill Pediatric Patient and SARS-CoV-2 Infection

Affiliations
Review

Critically Ill Pediatric Patient and SARS-CoV-2 Infection

Jozef Klučka et al. Children (Basel). .

Abstract

In December 2019 SARS-CoV-2 initiated a worldwide COVID-19 pandemic, which is still ongoing in 2022. Although adult elderly patients with chronic preexisting diseases had been identified as the most vulnerable group, COVID-19 has also had a significant impact on pediatric intensive care. Early in 2020, a new disease presentation, multisystemic inflammatory syndrome, was described in children. Despite the vaccination that is available for all age categories, due to its selection process, new viral mutations and highly variable vaccination rate, COVID-19 remains a significant clinical challenge in adult and pediatric intensive care in 2022.

Keywords: COVID-19; SARS-CoV-2; child; intensive care; management; pediatric.

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Conflict of interest statement

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

References

    1. Cascella M., Rajnik M., Aleem A., Dulebohn S.C., Di Napoli R. StatPearls. StatPearls Publishing; Treasure Island, FL, USA: 2022. Features, Evaluation, and Treatment of Coronavirus (COVID-19) - PubMed
    1. Kache S., Chisti M.J., Gumbo F., Mupere E., Zhi X., Nallasamy K., Nakagawa S., Lee J.H., Di Nardo M., de la Oliva P., et al. COVID-19 PICU guidelines: For high-and limited-resource settings. Pediatr. Res. 2020;88:705–716. doi: 10.1038/s41390-020-1053-9. - DOI - PMC - PubMed
    1. World Health Organization Coronavirus Disease 2019 (COVID-19): Situation Report. [(accessed on 5 February 2022)]. Available online: http://www.Who.Int/docs/default-source/coronaviruse/situation-reports.2.
    1. Riphagen S., Gomez X., Gonzalez-Martinez C., Wilkinson N., Theocharis P. Hyperinflammatory shock in children during COVID-19 pandemic. Lancet. 2020;395:1607–1608. doi: 10.1016/S0140-6736(20)31094-1. - DOI - PMC - PubMed
    1. Hu B., Guo H., Zhou P., Shi Z.L. Characteristics of SARS-CoV-2 and COVID-19. Nat. Rev. Microbiol. 2021;19:141–154. doi: 10.1038/s41579-020-00459-7. - DOI - PMC - PubMed

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