Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Oct;269(10):5647-5650.
doi: 10.1007/s00415-022-11130-x. Epub 2022 Apr 23.

Anti-MOG associated disease with intracranial hypertension after COVID-19 vaccination

Lina Jeantin  1 , Adèle Hesters  1 , Dorine Fournier  2 , Bénédicte Lebrun-Vignes  2 , Aurélie Méneret  1 , Caroline Papeix  1   3 , Valérie Touitou  4 , Elisabeth Maillart  5   6
Affiliations

Anti-MOG associated disease with intracranial hypertension after COVID-19 vaccination

Lina Jeantin et al. J Neurol. 2022 Oct.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare that there is no conflict of interest.

Figures

Fig. 1
Fig. 1
MRI and optical coherence tomography data. A–B Data from the first MRI showing white-matter FLAIR hyperintensities of the left posterior thalamus (panel A), left cerebral peduncle (panel B) (arrow heads). C–D Second MRI data showing white-matter FLAIR hyperintensities of the corpus callosum (panel C), and C2 myelitis (in T2-weighted images, panel D) (arrow heads). E–G Intracranial hypertension aspects with right lateral sinus stenosis (panel E), empty sella syndrome (panel F), and enlarged optic nerves sheaths (panel G) (arrow heads). H Neuritis and perineuritis of the optic nerves in T1-weighted post gadolinium sequences during the relapse as optic neuritis. (arrow heads). I and K horizontal tomography of the papilla for both eyes showing papilledema. J Optical coherence tomography data for the thickness of the retinal nerve fiber layer (normal distribution in green) showing increased thickness for both eyes
See this image and copyright information in PMC

References

    1. Ramanathan S, Dale RC, Brilot F. Anti-MOG antibody: the history, clinical phenotype, and pathogenicity of a serum biomarker for demyelination. Autoimmun Rev. 2016;15:307–324. doi: 10.1016/j.autrev.2015.12.004. - DOI - PubMed
    1. Kania K, Ambrosius W, Tokarz Kupczyk E, Kozubski W. Acute disseminated encephalomyelitis in a patient vaccinated against SARS-CoV-2. Ann Clin Transl Neurol. 2021 doi: 10.1002/acn3.51447. - DOI - PMC - PubMed
    1. Zuhorn F, Graf T, Klingebiel R, et al. Postvaccinal encephalitis after ChAdOx1 nCov -19. Ann Neurol. 2021;90:506–511. doi: 10.1002/ana.26182. - DOI - PMC - PubMed
    1. Mumoli L, Vescio V, Pirritano D, et al. ADEM anti-MOG antibody-positive after SARS-CoV2 vaccination. Neurol Sci. 2021 doi: 10.1007/s10072-021-05761-7. - DOI - PMC - PubMed
    1. Dams L, Kraemer M, Becker J. MOG-antibody-associated longitudinal extensive myelitis after ChAdOx1 nCoV-19 vaccination. Mult Scler. 2021 doi: 10.1177/13524585211057512. - DOI - PubMed