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Review
. 2022 Jun;62(2):167-174.
doi: 10.1007/s12088-022-01001-4. Epub 2022 Jan 29.

Nano-Therapeutics to Treat Acne Vulgaris

Affiliations
Review

Nano-Therapeutics to Treat Acne Vulgaris

Nayanika Chakraborty et al. Indian J Microbiol. 2022 Jun.

Abstract

Nanotechnology is a novel approach to dermatologic treatment. Nanomaterials are materials typically defined as less than 100 nm in size. As this size approaches molecular dimensions, the chemical and physical properties vastly change due to a relative increase in surface area to volume ratio. Unique and altered properties ensue, such as carbon becoming an electrical conductant in the nano form, and glass becoming a liquid. The interaction of nanoparticles with biota likewise changes. Novel therapeutics may be possible with the use of nanomaterials. Advantages of nanoparticles include the ability to overcome microbial resistance and potentially induce immunomodulatory effects. Engineered nanomaterials or the development of nano-therapeutics with photo-induced antibacterial propensity and immunomodulatory activities has the potential to open new prospects for the treatment of ubiquitous cutaneous diseases, such as acne vulgaris.

Keywords: Acne vulgaris; Nanodermatology; Nanotechnology; Phototherapy; Propionibacterium acnes.

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Conflict of interest statement

Conflict of interestThe authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
Nanomaterial based anti-acne formulations are synthesized for follicular and trans-follicular drug delivery
Fig. 2
Fig. 2
Schematic representation of various nano therapeutics applied in treatment for Acne vulgaris

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