Management of penetrating aortic ulcer and intramural hematoma in the thoracic aorta
- PMID: 35463695
- PMCID: PMC8980974
- DOI: 10.1007/s12055-022-01332-3
Management of penetrating aortic ulcer and intramural hematoma in the thoracic aorta
Abstract
Acute aortic syndrome is a broad clinical entity that encompasses several pathologies. Aortic dissection is a well-studied disorder, but the other most prominent disorders within the scope of acute aortic syndrome, penetrating aortic ulcer and intramural hematoma, are more nebulous in terms of their pathophysiology and treatment strategies. While patient risk factors, presenting symptoms, and medical and surgical management strategies are similar to those of aortic dissection, there are indeed nuanced differences unique to penetrating aortic ulcer and intramural hematoma that surgeons and acute care providers must consider while managing patients with these diagnoses. The aim of this review is to summarize patient demographics, pathophysiology, workup, and treatment strategies that are unique to penetrating aortic ulcer and intramural hematoma.
Keywords: Acute aortic syndrome; Intramural hematoma; Penetrating aortic ulcer.
© Indian Association of Cardiovascular-Thoracic Surgeons 2022.
Conflict of interest statement
Drs. Warner and Bhamidipadi have no conflicts of interest pertinent to this manuscript. Dr. Abraham is a paid consultant for the Medtronic Aortic Advisory Board, a paid consultant as an Advanced Aortic Intervention proctor, and a paid consultant for WL Gore as a Clinical Events Committee member for the Gore Conformable Stent Graft Clinical Trial.
Figures



Similar articles
-
Diagnosis and Management of Acute Aortic Syndromes: Dissection, Penetrating Aortic Ulcer, and Intramural Hematoma.Curr Cardiol Rep. 2022 Mar;24(3):209-216. doi: 10.1007/s11886-022-01642-3. Epub 2022 Jan 14. Curr Cardiol Rep. 2022. PMID: 35029783 Free PMC article. Review.
-
Midterm follow-up of penetrating ulcer and intramural hematoma of the aorta.J Thorac Cardiovasc Surg. 2002 Jun;123(6):1051-9. doi: 10.1067/mtc.2002.121681. J Thorac Cardiovasc Surg. 2002. PMID: 12063450
-
Penetrating Aortic Ulcer and Intramural Hematoma.Cardiovasc Intervent Radiol. 2019 Mar;42(3):321-334. doi: 10.1007/s00270-018-2114-x. Epub 2018 Nov 9. Cardiovasc Intervent Radiol. 2019. PMID: 30413917 Review.
-
Medically Managed Type A Thoracic Intramural Hematoma and Penetrating Aortic Ulcer.Cureus. 2022 Aug 8;14(8):e27776. doi: 10.7759/cureus.27776. eCollection 2022 Aug. Cureus. 2022. PMID: 36106244 Free PMC article.
-
Long-term behavior of aortic intramural hematomas and penetrating ulcers.J Thorac Cardiovasc Surg. 2016 Feb;151(2):361-72, 373.e1. doi: 10.1016/j.jtcvs.2015.09.012. Epub 2015 Sep 16. J Thorac Cardiovasc Surg. 2016. PMID: 26496809
Cited by
-
Aortic ulcerated plaque discovery following mesenteric infarction in a 60-year-old patient: a case report.Ann Med Surg (Lond). 2024 Jun 10;86(10):6125-6128. doi: 10.1097/MS9.0000000000002262. eCollection 2024 Oct. Ann Med Surg (Lond). 2024. PMID: 39359773 Free PMC article.
-
Endovascular Treatment for Aortic Diseases: Intercontinental Disparities.Curr Cardiol Rep. 2025 Jul 21;27(1):115. doi: 10.1007/s11886-025-02260-5. Curr Cardiol Rep. 2025. PMID: 40691402 Review.
References
-
- Korepta LM, Aulivola B. Aortic intramural hematomas and penetrating aortic ulcerations: indications for treatment versus surveillance. Endovascular Today. 2020;19:78–82.
-
- Lansman SL, Saunders PC, Malekan R, Spielvogel D. Acute aortic syndrome. J Thorac Cardiovasc Surg. 2010;140:S92–S97. - PubMed
-
- Stanson AW, Kazmier FJ, Hollier LH, et al. Penetrating atherosclerotic ulcers of the thoracic aorta: natural history and clinicopathologic correlations. Ann Vasc Surg. 1986;1:15–23. - PubMed
LinkOut - more resources
Full Text Sources