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Review
. 2022 Apr 6:9:835439.
doi: 10.3389/fcvm.2022.835439. eCollection 2022.

Related Risk Factors and Treatment Management of Psoriatic Arthritis Complicated With Cardiovascular Disease

Affiliations
Review

Related Risk Factors and Treatment Management of Psoriatic Arthritis Complicated With Cardiovascular Disease

Zhoulan Zheng et al. Front Cardiovasc Med. .

Abstract

Psoriatic arthritis (PsA) is a chronic autoimmune inflammatory joint disease related to psoriasis (PsO). The risk of PsA patients with cardiovascular disease (CVD) is significantly higher than that of the general population. At present, the relevant mechanism is not clear, chronic inflammation and traditional cardiovascular risk factors are the most important factors for the increased risk of CVD in PsA patients. Early assessment of the risk of PsA patients with CVD, and active control of the disease activity of PsA patients and intervention of traditional cardiovascular risk factors can delay the progression of CVD risk. This article reviews the epidemiology and pathogenesis between PsA and CVD, and reviews the latest developments in the risk assessment and management of CVD in PsA patients.

Keywords: cardiovascular disease; inflammation risk; psoriatic arthritis; traditional cardiovascular risk factors; treatment management.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Pathogenesis of psoriatic arthritis complicated with cardiovascular disease.

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References

    1. WHO . World Health Statistics Overview 2019: Monitoring Health for the SDGs, Sustainable Development Goals. Geneva: World Health Organization; (2019).
    1. Gottlieb A, Merola JF. Psoriatic arthritis for dermatologists. J Dermatolog Treat. (2020) 31:662–79. 10.1080/09546634.2019.1605142 - DOI - PubMed
    1. Lam SH, So H, Cheng IT, Li EK, Wong P, Li TK, et al. . Association of C-reactive protein and non-steroidal anti-inflammatory drugs with cardiovascular events in patients with psoriatic arthritis: a time-dependent Cox regression analysis. Ther Adv Musculoskelet Dis. (2021) 13:1759720X211027712. 10.1177/1759720X211027712 - DOI - PMC - PubMed
    1. Esposito M, Giunta A, Mazzotta A, Zangrilli A, Babino G, Bavetta M, et al. . Efficacy and safety of subcutaneous anti-tumor necrosis factor-alpha agents, etanercept and adalimumab, in elderly patients affected by psoriasis and psoriatic arthritis: an observational long-term study. Dermatology. (2012) 225:312–9. 10.1159/000345623 - DOI - PubMed
    1. Maximilian R, Garbe C, Petersen J, Augustin M, Kirsten N, Biermann MHC, et al. . Epidemiology, comorbidity and risk factors for psoriatic arthritis: a health insurance claims database analysis. Acta Derm Venereol. (2021) 101:adv00566. 10.2340/00015555-3879 - DOI - PMC - PubMed