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. 2022 Apr 14:2022:3918045.
doi: 10.1155/2022/3918045. eCollection 2022.

Cancer Burden in China during 1990-2019: Analysis of the Global Burden of Disease

Shu-Zhen Zhang  1 , Li Zhang  2 , Long Xie  1
Affiliations

Cancer Burden in China during 1990-2019: Analysis of the Global Burden of Disease

Shu-Zhen Zhang et al. Biomed Res Int. .

Abstract

This study reports the risk factors, trends, and burden of cancer in China from 1990 to 2019 from the Global Burden of Diseases. The incidence, mortality, and DALY of all cancers in China for the past 30 years were analyzed. In 2019, the age-standardized rates (ASRs) of cancer incidence, mortality, and DALY in China were 232.42/100 000, 136.72/100 000, and 3288.22/100 000, respectively. The five cancers with the highest age-standardized incidence rates were lung, stomach, colorectal, breast, and prostate cancers. From 1990 to 2019, the number of new cancer cases, deaths, and DALY increased by 168.78%, 86.89%, and 51.20%, respectively. The ASR increased by 22.21% for incidence and decreased by 19.01% and 27.19% for mortality and DALY, respectively, and their corresponding average annual percent change values were 0.71, -0.80, and -1.26, respectively. The main risk factors for cancer in China were smoking, air pollution, dietary factors, and alcohol use. From 1990 to 2019, the cancer incidence rate was on the rise, and cancer mortality and DALY rates were declining; however, these characteristics vary by cancer site. Therefore, current prevention strategies should be reoriented, and specific strategies for cancers in different sites should be established to prevent the increase in cancer cases.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Trend of cancer by crude incidence rate, mortality rate, and DALY in China, 1990–2019.
Figure 2
Figure 2
Risk factors of cancer contributing to DALYs in China, 2019.
See this image and copyright information in PMC

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References

    1. Bray F., Ferlay J., Soerjomataram I., Siegel R. L., Torre L. A., Ahmedin J. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a Cancer Journal for Clinicians . 2018;68(6):394–424. doi: 10.3322/caac.21492. - DOI - PubMed
    1. Chen W., Zheng R., Baade P. D., et al. Cancer statistics in China, 2015. Journal of Cancer Research and Clinical Oncology . 2016;66(2):115–132. doi: 10.3322/caac.21338. - DOI - PubMed
    1. Chen W., Sun K., Zheng R., et al. Cancer incidence and mortality in China, 2014. Chinese Journal of Cancer Research . 2018;30(1):1–12. doi: 10.21147/j.issn.1000-9604.2018.01.01. - DOI - PMC - PubMed
    1. Yang G., Wang Y., Zeng Y., et al. Rapid health transition in China, 1990-2010: findings from the Global Burden of Disease Study 2010. Lancet . 2013;381(9882):1987–2015. doi: 10.1016/S0140-6736(13)61097-1. - DOI - PMC - PubMed
    1. Zhou M., Wang H., Zhu J., et al. Cause-specific mortality for 240 causes in China during 1990-2013: a systematic subnational analysis for the Global Burden of Disease Study 2013. Lancet . 2016;387(10015):251–272. doi: 10.1016/S0140-6736(15)00551-6. - DOI - PubMed