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Review
. 2022 Apr 6:13:840245.
doi: 10.3389/fimmu.2022.840245. eCollection 2022.

Lactobacillus spp. for Gastrointestinal Health: Current and Future Perspectives

Elaine Dempsey  1   2 , Sinéad C Corr  2   3
Affiliations
Review

Lactobacillus spp. for Gastrointestinal Health: Current and Future Perspectives

Elaine Dempsey et al. Front Immunol. .

Abstract

In recent decades, probiotic bacteria have become increasingly popular as a result of mounting scientific evidence to indicate their beneficial role in modulating human health. Although there is strong evidence associating various Lactobacillus probiotics to various health benefits, further research is needed, in particular to determine the various mechanisms by which probiotics may exert these effects and indeed to gauge inter-individual value one can expect from consuming these products. One must take into consideration the differences in individual and combination strains, and conditions which create difficulty in making direct comparisons. The aim of this paper is to review the current understanding of the means by which Lactobacillus species stand to benefit our gastrointestinal health.

Keywords: gastrointestinal barrier; inflammation; lactobacillus; microbiota; probiotic.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Probiotic mechanisms of intestinal barrier enhancement.
Figure 2
Figure 2
Representation of the Lactobacillus cell surface structure including important effector molecules.
See this image and copyright information in PMC

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