SURPASSing the current dogma: is our framework shifting?
- PMID: 35468324
- PMCID: PMC10161145
- DOI: 10.1016/S2213-8587(22)00108-5
SURPASSing the current dogma: is our framework shifting?
Conflict of interest statement
VRA has served as a consultant for Applied Therapeutics, Fractyl, Novo Nordisk, Pfizer, and Sanofi; has a spouse who is employed by Janssen; and has had research support (institutional clinical trial contracts) from Applied Therapeutics/Medpace, Eli Lilly, Premier/Fractyl, Novo Nordisk, and Sanofi/Medpace. NPM declares no competing interests.
Comment on
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Efficacy of once-weekly tirzepatide versus once-daily insulin degludec on glycaemic control measured by continuous glucose monitoring in adults with type 2 diabetes (SURPASS-3 CGM): a substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial.Lancet Diabetes Endocrinol. 2022 Jun;10(6):407-417. doi: 10.1016/S2213-8587(22)00077-8. Epub 2022 Apr 22. Lancet Diabetes Endocrinol. 2022. PMID: 35468321 Clinical Trial.
References
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- Battelino T, Bergenstal RM, Rodríguez A, et al. Efficacy of once-weekly tirzepatide versus once-daily insulin degludec on glycaemic control measured by continuous glucose monitoring in adults with type 2 diabetes (SURPASS-3 CGM): a substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial. Lancet Diabetes Endocrinol 2022; published online April 22. 10.1016/S2213-8587(22)00077-8. - DOI - PubMed
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- Ludvik B, Giorgino F, Jódar E, et al. Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial. Lancet; 398: 583–98. - PubMed
-
- Draznin B, Aroda VR, Bakris G, et al. Glycemic targets: standards of medical care in diabetes—2022. Diabetes Care 2022; 45 (suppl 1): S83–96. - PubMed
-
- Aroda VR. A review of GLP-1 receptor agonists: evolution and advancement, through the lens of randomised controlled trials. Diabetes Obes Metab 2018; 20 (suppl 1): 22–33. - PubMed
-
- Frías JP. Tirzepatide: a glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) dual agonist in development for the treatment of type 2 diabetes. Expert Rev Endocrinol Metab 2020; 15: 379–94. - PubMed
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