Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Mar;27(1):265-274.
doi: 10.1007/s11325-022-02619-w. Epub 2022 Apr 25.

The independent and combined association of napping and night sleep duration with stroke in Chinese rural adults

Jing Yang #  1   2 , Xiaotian Liu #  2 , Zhihan Zhai  2 , Wei Liao  2 , Yaling He  2 , Xueyan Wu  2 , Chongjian Wang  2 , Chunyang Sun  3 , Yuqian Li  4   5
Affiliations

The independent and combined association of napping and night sleep duration with stroke in Chinese rural adults

Jing Yang et al. Sleep Breath. 2023 Mar.

Abstract

Background: Inappropriate sleep duration is a potential cause of stroke. But the effect of napping on stroke risk remains controversial and the interaction between night sleep and napping duration remains unclear. The objective of this study was to examine the independent and combined effects of napping and nocturnal sleep duration on stroke.

Methods: Subjects were derived from a rural cohort study in Henan. The Pittsburgh Sleep Quality Index (PSQI) was applied to identify nap duration and nocturnal sleep duration. Binary logistic regression was employed to indicate the dose-response relationships between naps, nocturnal sleep, total 24-h sleep duration, and stroke.

Results: Among the 37,341 participants (14,485 men), 2600 suffered from a stroke. The odds ratios (ORs) and 95% confidence level (CI) for stroke in the fully adjusted model were 1.37 (1.13-1.65) for men nappers compared to non-nappers. Compared to 7-8 h of sleep per day, night sleep durations < 6 h and ≥ 9 h and 24-h sleep duration ≥ 10 h were linked to increased odds of stroke in men. The ORs (95%CI) were 1.34 (1.06-1.69) in nocturnal sleep duration < 6 h, 1.30 (1.06-1.59) in nocturnal sleep duration ≥ 9 h, and 1.40 (1.15-1.71) in 24-h sleep duration ≥ 10 h in men. In addition, long naps and prolonged nocturnal sleep duration have a joint effect on stroke in the fully adjusted model.

Conclusion: The napping duration and nocturnal sleep duration have independently and jointly effects on stroke in rural populations. More research is required to explore the underlying mechanisms for this relationship.

Clinical trial registration: The Henan Rural Cohort Study has been registered on the Chinese Clinical Trial Register (Registration number: ChiCTR-OOC-15006699) ( http://www.chictr.org.cn/showproj.aspx?proj=11375 ).

Keywords: 24-h total sleep; Logistic regression; Napping duration; Night sleep duration; Stroke.

PubMed Disclaimer

References

    1. Wu S, Wu B, Liu M, Chen Z, Wang W, Anderson CS, Sandercock P, Wang Y, Huang Y, Cui L et al (2019) Stroke in China: advances and challenges in epidemiology, prevention, and management. Lancet Neurol 18(4):394–405. https://doi.org/10.1016/S1474-4422(18)30500-3 - DOI - PubMed
    1. Liu J, Shi Z, Bai R, Zheng J, Ma S, Wei J, Liu G, Wang Y (2020) Temporal, geographical and demographic trends of stroke prevalence in China: a systematic review and meta-analysis. Ann Transl Med 8(21):1432. https://doi.org/10.21037/atm-19-4342 - DOI - PubMed - PMC
    1. Feigin VL, Roth GA, Naghavi M, Parmar P, Krishnamurthi R, Chugh S, Mensah GA, Norrving B, Shiue I, Ng M et al (2016) Global burden of stroke and risk factors in 188 countries, during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet Neurol 15(9):913–924. https://doi.org/10.1016/S1474-4422(16)30073-4 - DOI - PubMed
    1. Jin X, Chen H, Li Y, Xu W, Chen X, Tian L, Teng W (2021) Association between daytime napping and stroke: A dose-response meta-analysis. J Sleep Res 30:e13366. https://doi.org/10.1111/jsr.13366 - DOI - PubMed
    1. Fang J, Wheaton AG, Ayala C (2014) Sleep duration and history of stroke among adults from the USA. J Sleep Res 23(5):531–537. https://doi.org/10.1111/jsr.12160 - DOI - PubMed - PMC

LinkOut - more resources