Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Sep 1;42(5):602-605.
doi: 10.3343/alm.2022.42.5.602.

Serial Analysis and Comparison of Mutation Profiles in Decitabine-treated Myeloid Sarcoma and Subsequent Acute Myeloid Leukemia Using Next-Generation Sequencing

Hee Sue Park  1   2 , Seung Myoung Son  3   4 , Jihyun Kwon  5   6
Affiliations

Serial Analysis and Comparison of Mutation Profiles in Decitabine-treated Myeloid Sarcoma and Subsequent Acute Myeloid Leukemia Using Next-Generation Sequencing

Hee Sue Park et al. Ann Lab Med. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

CONFLICTS OF INTEREST

The authors declare no conflicts of interest.

Figures

Fig. 1
Fig. 1
Computed tomography and pathologic findings of the MS mass. (A, B) Computed tomography reveals the extent of soft tissue lesion surrounding the paraaortic and retrocrural spaces. (C) Pathological findings of the MS tissue (hematoxylin and eosin staining). (D) Immunostaining for myeloperoxidase (original magnification, ×200; scale bar, 50 μm). Abbreviation: MS, myeloid sarcoma.
See this image and copyright information in PMC

References

    1. Avni B, Koren-Michowitz M. Myeloid sarcoma: current approach and therapeutic options. Ther Adv Hematol. 2011;2:309–16. doi: 10.1177/2040620711410774. - DOI - PMC - PubMed
    1. Li Z, Stölzel F, Onel K, Sukhanova M, Mirza MK, Yap KL, et al. Next-generation sequencing reveals clinically actionable molecular markers in myeloid sarcoma. Leukemia. 2015;29:2113–6. doi: 10.1038/leu.2015.81. - DOI - PMC - PubMed
    1. Greenland NY, Van Ziffle JA, Liu YC, Qi Z, Prakash S, Wang L. Genomic analysis in myeloid sarcoma and comparison with paired acute myeloid leukemia. Hum Pathol. 2021;108:76–83. doi: 10.1016/j.humpath.2020.11.005. - DOI - PubMed
    1. Kashofer K, Gornicec M, Lind K, Caraffini V, Schauer S, Beham-Schmid C, et al. Detection of prognostically relevant mutations and translocations in myeloid sarcoma by next generation sequencing. Leuk Lymphoma. 2018;59:501–4. doi: 10.1080/10428194.2017.1339879. - DOI - PMC - PubMed
    1. Werstein B, Dunlap J, Cascio MJ, Ohgami RS, Fan G, Press R, et al. Molecular discordance between myeloid sarcomas and concurrent bone marrows occurs in actionable genes and is associated with worse overall survival. J Mol Diagn. 2020;22:338–45. doi: 10.1016/j.jmoldx.2019.11.004. - DOI - PubMed

MeSH terms

LinkOut - more resources