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. 2022 May;29(3):e12746.
doi: 10.1111/xen.12746. Epub 2022 Apr 26.

Commentary on achievement of first life-saving xenoheart transplant

Martine Rothblatt  1
Affiliations

Commentary on achievement of first life-saving xenoheart transplant

Martine Rothblatt. Xenotransplantation. 2022 May.

Abstract

Two months of post-transplant survival were achieved in an end-stage heart disease patient with a porcine heart from a pig whose genome had been modified in 10 of its genes. This first-ever life-saving cardiac xenotransplantation was the result of decades of work and close coordination by researchers in genetic engineering, animal cloning, immunology, ex vivo organ perfusion, and thoracic surgery.

Keywords: cardiac; cloning; genetic engineering; xenograft; xenoheart.

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References

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