Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Published Erratum
. 2022 Apr 26;119(17):e2204610119.
doi: 10.1073/pnas.2204610119. Epub 2022 Apr 26.

Correction for Morton et al., Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

No authors listed
Published Erratum

Correction for Morton et al., Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

No authors listed. Proc Natl Acad Sci U S A. .
No abstract available

PubMed Disclaimer

Figures

Fig. 2.
Fig. 2.
Senescence program is activated in KrasG12D-expressing cells in the normal pancreas but not in pancreatic tumors. (A–C) β-Galactosidase staining at pH 6, (D–F) p53 immunohistochemical staining, (G–I) p21 immunohistochemical staining, and (J–L) MCM2 immunohistochemical staining, in sections of frozen (β-galactosidase) or formalin-fixed paraffin-embedded pancreatic tissue. (A, D, G, and J) Normal pancreatic ducts in pancreata harvested from 6-week-old Pdx1-Cre-GFP, LSL-KrasG12D/+ (KC) mice, (B, E, H, and K) PanIN lesions in pancreata harvested from 6-week-old KC mice, and (C, F, I, and L) pancreatic ductal adenocarcinoma harvested from Pdx1-Cre-GFP, LSL-KrasG12D/+, LSL-Trp53R172H/+ (KPC) mice. Arrowheads indicate areas where p21 up-regulation has been lost.
See this image and copyright information in PMC

Erratum for

Publication types