Immunogenomic classification of hepatocellular carcinoma patients for immune check-point inhibitors therapy: cui bono?

Ruben Hernaez^{1

2

3}, Matias A Avila^{4

5

6}

Affiliations

¹ Gastroenterology and Hepatology, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USA ruben.hernaez@bcm.edu.
² Center for Innovations in Quality, Effectiveness and Safety, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USA.
³ Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas, USA.
⁴ Hepatology, CIMA-University of Navarra, Pamplona, Spain.
⁵ Instituto de Investigaciones Sanitarias de Navarra IdiSNA, Pamplona, Spain.
⁶ CIBERehd, Instituto de Salud Carlos III, Madrid, Spain.

Comment

Ruben Hernaez et al. Gut. 2023 Jan.

. 2023 Jan;72(1):7-9.

doi: 10.1136/gutjnl-2022-327132. Epub 2022 Apr 26.

Ruben Hernaez^{1

2

3}, Matias A Avila^{4

5

6}

¹ Gastroenterology and Hepatology, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USA ruben.hernaez@bcm.edu.
² Center for Innovations in Quality, Effectiveness and Safety, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USA.
³ Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas, USA.
⁴ Hepatology, CIMA-University of Navarra, Pamplona, Spain.
⁵ Instituto de Investigaciones Sanitarias de Navarra IdiSNA, Pamplona, Spain.
⁶ CIBERehd, Instituto de Salud Carlos III, Madrid, Spain.

No abstract available

Keywords: HEPATOCELLULAR CARCINOMA; IMMUNOLOGY IN HEPATOLOGY; IMMUNOTHERAPY.

Conflict of interest statement

Competing interests: None declared.

Inflamed and non-inflamed classes of HCC: a revised immunogenomic classification.
Montironi C, Castet F, Haber PK, Pinyol R, Torres-Martin M, Torrens L, Mesropian A, Wang H, Puigvehi M, Maeda M, Leow WQ, Harrod E, Taik P, Chinburen J, Taivanbaatar E, Chinbold E, Solé Arqués M, Donovan M, Thung S, Neely J, Mazzaferro V, Anderson J, Roayaie S, Schwartz M, Villanueva A, Friedman SL, Uzilov A, Sia D, Llovet JM. Montironi C, et al. Gut. 2023 Jan;72(1):129-140. doi: 10.1136/gutjnl-2021-325918. Epub 2022 Feb 23. Gut. 2023. PMID: 35197323 Free PMC article.