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. 2022 Apr 20;48(2):e20210478.
doi: 10.36416/1806-3756/e20210478.

Pulmonary metastasis of osteosarcoma: multiple presentations in a single patient

[Article in English, Portuguese]
Jéssica Albuquerque M Silva  1 , Edson Marchiori  2 , Fabiane Carvalho de Macedo  1 , Paulo Ricardo Garcia da Silva  1 , Viviane Brandão Amorim  1   3
Affiliations

Pulmonary metastasis of osteosarcoma: multiple presentations in a single patient

[Article in English, Portuguese]
Jéssica Albuquerque M Silva et al. J Bras Pneumol. .
No abstract available

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Figures

Figure 1
Figure 1. Frontal and lateral radiographs (A) of the right distal femur (taken in February 2019) showing a juxtacortical mass with a Codman triangle, periosteal reaction (white arrows), and calcification foci. The femoral metaphysis is involved and the tumor extends into the diaphysis. Chest CT image (B) obtained during neoadjuvant chemotherapy (in April 2019). Axial view showing multiple cavitated nodules, some of which are peripheral (white arrows). Bilateral pneumothorax can also be observed. Histological features (C) of a pulmonary nodule: a neoplasm composed of spindle cells and atypical epithelioid cells with an osteoid matrix surrounded by giant cells, similar to osteoclasts. Hematoxylin and eosin staining, original magnification ×40. Axial chest CT image (D) obtained during second-line chemotherapy (in October 2019) showing a nodular opacity in the left lower lobe with a ground-glass halo (white arrow), suggesting hemorrhagic metastases. Axial chest CT image (E) obtained with the mediastinal window during third-line chemotherapy (in March 2020) showing multiple bilateral masses with soft-tissue density. Note also the calcification foci (white arrows) and pleural effusion (asterisk).
See this image and copyright information in PMC

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