LAG3 disrupts the TCR signal by local acidification
- PMID: 35477982
- DOI: 10.1038/s41590-022-01196-0
LAG3 disrupts the TCR signal by local acidification
Comment on
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LAG3 associates with TCR-CD3 complexes and suppresses signaling by driving co-receptor-Lck dissociation.Nat Immunol. 2022 May;23(5):757-767. doi: 10.1038/s41590-022-01176-4. Epub 2022 Apr 18. Nat Immunol. 2022. PMID: 35437325 Free PMC article.
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