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Review
. 2022 Apr;6(4):327-338.
doi: 10.1038/s41551-022-00885-3. Epub 2022 Apr 27.

Opportunities and challenges in cardiac tissue engineering from an analysis of two decades of advances

Richard Z Zhuang #  1 , Roberta Lock #  1 , Bohao Liu #  2 , Gordana Vunjak-Novakovic  3   4   5
Affiliations
Review

Opportunities and challenges in cardiac tissue engineering from an analysis of two decades of advances

Richard Z Zhuang et al. Nat Biomed Eng. 2022 Apr.

Abstract

Engineered human cardiac tissues facilitate progress in regenerative medicine, disease modelling and drug development. In this Perspective, we reflect on the most notable advances in cardiac tissue engineering from the past two decades by analysing pivotal studies and critically examining the most consequential developments. This retrospective analysis led us to identify key milestones and to outline a set of opportunities, along with their associated challenges, for the further advancement of engineered human cardiac tissues.

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References

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