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. 2022 Apr 25;12(20):12471-12476.
doi: 10.1039/d2ra01629j. eCollection 2022 Apr 22.

Preparation of quinazolinones using biosynthesized silver nanoparticles

Javad Safaei-Ghomi  1 , Yasir Waleed Abdulhameed  2 , Zianos Alisavari  1 , Baram Ahmed Hamah Ameen  3 , Seyyed Mohammad Ebrahimi  1
Affiliations

Preparation of quinazolinones using biosynthesized silver nanoparticles

Javad Safaei-Ghomi et al. RSC Adv. .

Abstract

A silver nanocatalyst has been used as an effective catalyst for the preparation of quinazolinones under reflux conditions in ethanol. The catalyst was characterized by UV-VIS, FT-IR, XRD, SEM and EDS. Amongst the many benefits of this method are atom economy, reusability of the catalyst, low catalyst loading, applicability to a wide range of substrates, high yields of products, environmental friendliness and easy separation of products. Silver nanoparticles (Ag NPs) were prepared using Echium amoenum extract. The structures of the prepared quinazolinones were fully characterized by 1H and 13C NMR, FT-IR spectra and elemental analysis.

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Conflict of interest statement

There are no conflicts to declare.

Figures

Scheme 1
Scheme 1. Synthesis of quinazolinones using biosynthesized Ag NPs.
Fig. 1
Fig. 1. UV-VIS of Ag NPs and plant extract.
Fig. 2
Fig. 2. XRD of Ag NPs.
Fig. 3
Fig. 3. SEM of Ag NPs.
Fig. 4
Fig. 4. EDS of the nanocatalyst.
Fig. 5
Fig. 5. FT-IR of Ag NPs synthesized using Echium amoenum extract.
Fig. 6
Fig. 6. Reusability of Ag NPs as a catalyst for the synthesis of 4f.
Scheme 2
Scheme 2. Proposed mechanism for the synthesis of quinazolinones.
See this image and copyright information in PMC

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