Junctophillin-2: Coupling Hopes for Cardiac Gene Therapy to Gene Transcription

Peter Wright^{1

2}, Julia Gorelik²

Affiliations

¹ School of Life and Health Sciences, University of Roehampton, London, United Kingdom (P.W.).
² National Heart, and Lung Institute (NHLI), Faculty of Medicine, Imperial College London, United Kingdom (P.W., J.G.).

Free article

Editorial

Peter Wright et al. Circ Res. 2022.

Free article

. 2022 Apr 29;130(9):1318-1320.

doi: 10.1161/CIRCRESAHA.122.321066. Epub 2022 Apr 28.

Peter Wright^{1

2}, Julia Gorelik²

¹ School of Life and Health Sciences, University of Roehampton, London, United Kingdom (P.W.).
² National Heart, and Lung Institute (NHLI), Faculty of Medicine, Imperial College London, United Kingdom (P.W., J.G.).

No abstract available

Keywords: Editorials; genetic therapy; heart failure; phenotype; phosphorylation; sarcoplasmic reticulum.

Comment on

Gene Therapy With the N-Terminus of Junctophilin-2 Improves Heart Failure in Mice.
Wang J, Shi Q, Wang Y, Dawson LW, Ciampa G, Zhao W, Zhang G, Chen B, Weiss RM, Grueter CE, Hall DD, Song LS. Wang J, et al. Circ Res. 2022 Apr 29;130(9):1306-1317. doi: 10.1161/CIRCRESAHA.121.320680. Epub 2022 Mar 23. Circ Res. 2022. PMID: 35317607 Free PMC article.