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Case Reports
. 1987 Mar 1;59(6):705-7.
doi: 10.1016/0002-9149(87)91199-4.

Liver transplantation for treatment of cardiovascular disease: comparison with medication and plasma exchange in homozygous familial hypercholesterolemia

J M Hoeg, T E Starzl, H B Brewer Jr
Case Reports

Liver transplantation for treatment of cardiovascular disease: comparison with medication and plasma exchange in homozygous familial hypercholesterolemia

J M Hoeg et al. Am J Cardiol. .
No abstract available

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Figures

FIGURE 1
FIGURE 1
The effects of various treatment regimens on the plasma lipid and lipoprotein concentrations in homozygous familial hypercholesterolemia. Error bars indicate the mean ± standard error of the mean of 3 to 5 replicate samples during the indicated treatment regimen. To convert these values to millimoles per liter, multiply the value by 0.026.
FIGURE 2
FIGURE 2
Regression of tuberous xanthomas of the hands and elbows 2 and 6 months after liver transplantation. Cyclosporine-induced hirsutism is also evident by 6 months after transplantation.
See this image and copyright information in PMC

References

    1. Brown MS, Goldstein JL. A receptor-mediated pathway for cholesterol homeostasis. Science. 1986;232:34–47. - PubMed
    1. Goldstein JL, Brown MS. Familial Hypercholesterolemia. In: Stanbury JB, Wyngaarden JB, Fredrickson DS, Goldstein JL, Brown MS, editors. The Metabolic Basis of Inherited Disease. New York: McGraw Hill; 1983. pp. 672–712.
    1. Sprecher DL, Schaefer EJ, Kent KM, Gregg RE, Zech LA, Hoeg JM, McManus B, Roberts WC, Brewer HB., Jr Cardiovascular features of homozygous familial hypercholesterolemia: analysis of 16 patients. Am J Cardiol. 1984;54:20–30. - PubMed
    1. Hoeg JM, Demosky SJ, Jr, Gregg RE, Schaefer EJ, Brewer HB., Jr Hepatic receptors for low density lipoproteins and apolipoprotein E are genetically and physiologically distinct in man. Science. 1985;227:759–761. - PubMed
    1. Hoeg JM, Edge SB, Demosky SJ, Jr, Starzl TE, Triche T, Gregg RS, Brewer HB., Jr Metabolism of low density lipoproteins by cultured hepatocytes from normal and homozygous familial hypercholesterolemic subjects. Biochem Biophys Acta. 1986;876:647–657. - PMC - PubMed

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