Comparing treatment outcomes of various intracranial bifurcation aneurysms locations using the Woven EndoBridge (WEB) device

Nimer Adeeb¹, Mahmoud Dibas², Jose Danilo Bengzon Diestro³, Kevin Phan², Hugo H Cuellar-Saenz⁴, Ahmad Sweid⁵, Sovann V Lay⁶, Adrien Guenego⁶, Assala Aslan⁴, Leonardo Renieri⁷, Sri Hari Sundararajan⁸, Guillaume Saliou⁹, Markus Möhlenbruch¹⁰, Robert W Regenhardt¹¹, Justin E Vranic¹¹, Ivan Lylyk¹², Paul M Foreman¹³, Jay A Vachhani¹³, Vedran Župančić¹⁴, Muhammad U Hafeez¹⁵, Caleb Rutledge¹⁶, Muhammad Waqas¹⁷, Vincent M Tutino¹⁷, James D Rabinov¹¹, Yifan Ren¹⁸, Clemens M Schirmer¹⁹, Mariangela Piano²⁰, Anna L Kuhn²¹, Caterina Michelozzi²², Stephanie Elens²³, Robert M Starke²⁴, Ameer Hassan²⁵, Arsalaan Salehani²⁶, Alex Brehm²⁷, MajdEddin MohammedAli⁴, Jesse Jones²⁶, Marios Psychogios²⁷, Julian Spears³, Boris Lubicz²³, Pietro Panni²², Ajit S Puri²¹, Guglielmo Pero²⁰, Christoph J Griessenauer^{19

28}, Hamed Asadi¹⁸, Adnan Siddiqui¹⁷, Andrew Ducruet¹⁶, Felipe C Albuquerque¹⁶, Rose Du², Peter Kan¹⁵, Vladimir Kalousek¹⁴, Pedro Lylyk¹², Christopher J Stapleton¹¹, Srikanth Boddu⁸, Jared Knopman⁸, Mohammad A Aziz-Sultan², Nicola Limbucci⁷, Pascal Jabbour⁵, Christophe Cognard⁶, Aman B Patel¹¹, Adam A Dmytriw^{2

11}

Affiliations

¹ Departments of Neurosurgery and Neurointerventional Surgery, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA nimer_adeeb@hotmail.com.
² Neuroradiology and Neurosurgical Services, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
³ Department of Diagnostic and Therapeutic Neuroradiology, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
⁴ Departments of Neurosurgery and Neurointerventional Surgery, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
⁵ Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
⁶ Interventional Neuroradiology Department, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.
⁷ Interventistica Neurovascolare, Ospedale Careggi di Firenze, Florence, Italy.
⁸ Neurosurgery and Interventional Neuroradiology, New York Presbyterian Hospital, Weill Cornell School of Medicine, New York, New York, USA.
⁹ Department of Diagnostic and Interventional Radiology, Centre Hospitalier Universitaire Vaudois, Lausanne, Vaud, Switzerland.
¹⁰ Department of Neuroradiology, University of Heidelberg, Heidelberg, Germany.
¹¹ Neuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston, MA, USA.
¹² Equipo de Neurocirugía Endovascular y Radiología Intervencionista, Clínica La Sagrada Familia, Buenos Aires, Argentina.
¹³ Neurosurgery Department, Orlando Health Neuroscience and Rehabilitation Institute, Orlando, FL, USA.
¹⁴ Department of Radiology, Clinical Hospital Center 'Sisters of Mercy', Zagreb, Croatia.
¹⁵ Department of Neurosurgery, UTMB and Baylor School of Medicine, Houston, TX.
¹⁶ Department of Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona, USA.
¹⁷ Department of Neurosurgery, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York, USA.
¹⁸ Neurointervention Service, Department of Radiology, Austin Health, Heidelberg, Victoria, Australia.
¹⁹ Departments of Neurosurgery and Radiology, Geisinger Hospital, Danville, Virginia, USA.
²⁰ Department of Neuroradiology, Ospedale Niguarda Ca' Granda, Milano, Italy.
²¹ Department of Radiology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
²² Interventistica Neurovascolare, Ospedale San Raffaele, Milano, Italy.
²³ Department of Interventional Neuroradiology, Erasmus Hospital, Bruxelles, Bruxelles, Belgium.
²⁴ Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.
²⁵ Deparment of Neuroscience, Valley Baptist Neuroscience Institute, Harlingen, TX, USA.
²⁶ Department of Neurosurgery, UAB Hospital, Birmingham, Alabama, USA.
²⁷ Department of Neuroradiology, Clinic of Radiology and Nuclear Medicine, University Hospital Basel, Basel, Switzerland.
²⁸ Department of Neurosurgery, Christian Doppler Klinik, Paracelsus Medical University, Salzburg, Austria.

PMID: 35483912
DOI: 10.1136/neurintsurg-2022-018694

Comparing treatment outcomes of various intracranial bifurcation aneurysms locations using the Woven EndoBridge (WEB) device

Nimer Adeeb et al. J Neurointerv Surg. 2023 Jun.

. 2023 Jun;15(6):558-565.

doi: 10.1136/neurintsurg-2022-018694. Epub 2022 Apr 28.

Authors

Affiliations

¹ Departments of Neurosurgery and Neurointerventional Surgery, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA nimer_adeeb@hotmail.com.
² Neuroradiology and Neurosurgical Services, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
³ Department of Diagnostic and Therapeutic Neuroradiology, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
⁴ Departments of Neurosurgery and Neurointerventional Surgery, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
⁵ Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
⁶ Interventional Neuroradiology Department, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.
⁷ Interventistica Neurovascolare, Ospedale Careggi di Firenze, Florence, Italy.
⁸ Neurosurgery and Interventional Neuroradiology, New York Presbyterian Hospital, Weill Cornell School of Medicine, New York, New York, USA.
⁹ Department of Diagnostic and Interventional Radiology, Centre Hospitalier Universitaire Vaudois, Lausanne, Vaud, Switzerland.
¹⁰ Department of Neuroradiology, University of Heidelberg, Heidelberg, Germany.
¹¹ Neuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston, MA, USA.
¹² Equipo de Neurocirugía Endovascular y Radiología Intervencionista, Clínica La Sagrada Familia, Buenos Aires, Argentina.
¹³ Neurosurgery Department, Orlando Health Neuroscience and Rehabilitation Institute, Orlando, FL, USA.
¹⁴ Department of Radiology, Clinical Hospital Center 'Sisters of Mercy', Zagreb, Croatia.
¹⁵ Department of Neurosurgery, UTMB and Baylor School of Medicine, Houston, TX.
¹⁶ Department of Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona, USA.
¹⁷ Department of Neurosurgery, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York, USA.
¹⁸ Neurointervention Service, Department of Radiology, Austin Health, Heidelberg, Victoria, Australia.
¹⁹ Departments of Neurosurgery and Radiology, Geisinger Hospital, Danville, Virginia, USA.
²⁰ Department of Neuroradiology, Ospedale Niguarda Ca' Granda, Milano, Italy.
²¹ Department of Radiology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
²² Interventistica Neurovascolare, Ospedale San Raffaele, Milano, Italy.
²³ Department of Interventional Neuroradiology, Erasmus Hospital, Bruxelles, Bruxelles, Belgium.
²⁴ Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.
²⁵ Deparment of Neuroscience, Valley Baptist Neuroscience Institute, Harlingen, TX, USA.
²⁶ Department of Neurosurgery, UAB Hospital, Birmingham, Alabama, USA.
²⁷ Department of Neuroradiology, Clinic of Radiology and Nuclear Medicine, University Hospital Basel, Basel, Switzerland.
²⁸ Department of Neurosurgery, Christian Doppler Klinik, Paracelsus Medical University, Salzburg, Austria.

PMID: 35483912
DOI: 10.1136/neurintsurg-2022-018694

Abstract

Background: The Woven EndoBridge (WEB) device has Food and Drug Administration approval for treatment of wide-necked intracranial bifurcation aneurysms. The WEB device has been shown to result in adequate occlusion in bifurcation aneurysms overall, but its usefulness in the individual bifurcation locations has been evaluated separately only in few case series, which were limited by small sample sizes.

Objective: To compare angiographic and clinical outcomes after treatment of bifurcation aneurysms at various locations, including anterior communicating artery (AComA), anterior cerebral artery (ACA) bifurcation distal to AComA, basilar tip, internal carotid artery (ICA) bifurcation, and middle cerebral artery (MCA) bifurcation aneurysms using the WEB device.

Methods: A retrospective cohort analysis was conducted at 22 academic institutions worldwide to compare treatment outcomes of patients with intracranial bifurcation aneurysms using the WEB device. Data include patient and aneurysm characteristics, procedural details, angiographic and functional outcomes, and complications.

Results: A total of 572 aneurysms were included. MCA (36%), AComA (35.7%), and basilar tip (18.9%) aneurysms were most common. The rate of adequate aneurysm occlusion was significantly higher for basilar tip (91.6%) and ICA bifurcation (96.7%) aneurysms and lower for ACA bifurcation (71.4%) and AComA (80.6%) aneurysms (p=0.04).

Conclusion: To our knowledge, this is the most extensive study to date that compares the treatment of different intracranial bifurcation aneurysms using the WEB device. Basilar tip and ICA bifurcation aneurysms showed significantly higher rates of aneurysm occlusion than other locations.

Keywords: Aneurysm.

PubMed Disclaimer

Conflict of interest statement

Competing interests: The following authors serve on the editorial board of JNIS, JDBD, AG, AFD, FCA, and PK.

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
- HighWire
- Ovid Technologies, Inc.
Medical
- MedlinePlus Health Information
Miscellaneous
- NCI CPTAC Assay Portal

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Comparing treatment outcomes of various intracranial bifurcation aneurysms locations using the Woven EndoBridge (WEB) device

Affiliations

Comparing treatment outcomes of various intracranial bifurcation aneurysms locations using the Woven EndoBridge (WEB) device

Authors

Affiliations

Abstract

Conflict of interest statement

MeSH terms

LinkOut - more resources

Full Text Sources

Medical

Miscellaneous