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. 2022 Jun;52(6):806-811.
doi: 10.1111/cea.14137. Epub 2022 May 10.

Probiotic peanut oral immunotherapy is associated with long-term persistence of 8-week sustained unresponsiveness and long-lasting quality-of-life improvement

Paxton Loke  1   2   3   4 , Kuang-Chih Hsiao  1   5   6 , Adriana Chebar Lozinsky  1 , Sarah E Ashley  1   2   4 , Melanie Lloyd  1   4 , Sigrid Pitkin  1 , Christine Jean Axelrad  1 , Kaushala S Jayawardana  7 , Dean Tey  1   4 , Ee Lyn Su  1   4 , Marnie Robinson  1   4 , Agnes S Y Leung  1   8 , Audrey Dunn Galvin  9 , Mimi L K Tang  1   2   4
Affiliations

Probiotic peanut oral immunotherapy is associated with long-term persistence of 8-week sustained unresponsiveness and long-lasting quality-of-life improvement

Paxton Loke et al. Clin Exp Allergy. 2022 Jun.
No abstract available

Keywords: Peanut allergy; health-related quality of life; oral immunotherapy; probiotic and peanut oral immunotherapy; sustained unresponsiveness.

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References

REFERENCES

    1. Wang Y, Peters RL, Perrett KP, et al. Community-based adverse food reactions and anaphylaxis in children with IgE-mediated food allergy at age 6 years: a population-based study. J Allergy Clin Immunol Pract. 2020;8:3515-3524.
    1. Chinthrajah RS, Purington N, Andorf S, et al. Sustained outcomes in oral immunotherapy for peanut allergy (POISED study): a large, randomised, double-blind, placebo-controlled, phase 2 study. Lancet. 2019;394:1437-1449.
    1. Chu DK, Wood RA, French S, et al. Oral immunotherapy for peanut allergy (PACE): a systematic review and meta-analysis of efficacy and safety. Lancet. 2019;393:2222-2232.
    1. Tang ML, Ponsonby AL, Orsini F, et al. Administration of a probiotic with peanut oral immunotherapy: A randomized trial. J Allergy Clin Immunol. 2015;135:737-744.
    1. Hsiao KC, Ponsonby AL, Axelrad C, Pitkin S, Tang MLK. PPOIT study Team. Long-term clinical and immunological effects of probiotic and peanut oral immunotherapy after treatment cessation: 4-year follow-up of a randomised, double-blind, placebo-controlled trial. Lancet Child Adolesc Health. 2017;1:97-105.

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