Pro-inflammatory concerns with lipid nanoparticles
- PMID: 35487214
- PMCID: PMC9047613
- DOI: 10.1016/j.ymthe.2022.04.011
Pro-inflammatory concerns with lipid nanoparticles
Comment on
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IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines.Nat Immunol. 2022 Apr;23(4):532-542. doi: 10.1038/s41590-022-01160-y. Epub 2022 Mar 24. Nat Immunol. 2022. PMID: 35332327
References
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- Pardi N., Hogan M.J., Naradikian M.S., Parkhouse K., Cain D.W., Jones L., Moody M.A., Verkerke H.P., Myles A., Willis E., et al. Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses. J. Exp. Med. 2018;215:1571–1588. doi: 10.1084/jem.20171450. - DOI - PMC - PubMed
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