Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 May;26(2):313-322.
doi: 10.1016/j.cld.2022.01.011. Epub 2022 Apr 1.

Simultaneous Liver-Kidney Transplantation

Affiliations
Review

Simultaneous Liver-Kidney Transplantation

Gayatri Nair et al. Clin Liver Dis. 2022 May.

Abstract

End-stage kidney disease (ESKD) after liver transplantation is associated with high morbidity and mortality. This increase in mortality can be offset by performing a kidney transplant at the time of the liver transplant in select cases. Accordingly, Margreiter and colleague; s performed the first simultaneous liver-kidney (SLK) transplant in 1983. The number of SLK transplants has increased by more than 300% since then. In 1990%, 1.7% of all liver transplants in the United States were SLK transplants which increased to 9.9% by 2016. This steep increase was likely due to the implementation of the model of end-stage liver disease (MELD) scoring system in 2002, which is heavily weighted by serum creatinine.

Keywords: End-stage kidney disease; Liver transplantation; Liver–kidney transplantation; end-stage liver disease.

PubMed Disclaimer