Outcomes and Effects of 250-cm Biliopancreatic Limb One Anastomosis Gastric Bypass in Patients with BMI > 50 kg/m2 with Total Bowel Length > 6 m: a 2-Year Follow-up
- PMID: 35488110
- PMCID: PMC9276573
- DOI: 10.1007/s11695-022-06078-w
Outcomes and Effects of 250-cm Biliopancreatic Limb One Anastomosis Gastric Bypass in Patients with BMI > 50 kg/m2 with Total Bowel Length > 6 m: a 2-Year Follow-up
Abstract
Background: There is a controversy on the suitable bariatric procedure for patients with BMI > 50 kg/m2. Many surgeons prefer the Roux en-Y gastric bypass (RYGB) while others resort to long biliopancreatic limb (BPL) one anastomosis gastric bypass (OAGB).
Methods: This study included patients with BMI > 50 kg/m2 who underwent 250-cm BPL OAGB with total bowel length (TBL) > 6 m and completed 24-month follow-up from July 2015 to November 2021. Demographic data with preoperative weight, BMI, hypertension (HTN), DM (HbA1C), Hb, iron, calcium, albumin, vitamin D, and parathormone levels (PTH) were recorded. Operative time, total bowel length (TBL), residual length (RBL), complications and postoperative weight, BMI, % of total weight loss (%TWL), HTN, DM, and alkaline reflux as well as Hb, iron, calcium, albumin, vitamin D, and PTH levels were recorded at 6, 12, 18, and 24 months.
Results: OAGB had a significant decrease in weight, BMI (25.6 ± 3.4 kg/m2 at 24 months) with %TWL of 48 ± 5% at 24 months. TBL and RBL were 6.7 ± 0.65 and 4.2 ± 0.65 m respectively. %BL (RBL/TBL*100) was 62.4 ± 3.3%. The HbA1C, HTN, and alkaline reflux incidence were 5.5 ± 0.29 gm%, 1.4%, and 3.7% respectively at 24 months. Hb, iron, calcium, albumin, and vitamin D showed a significant decrease but still within normal range, and PTH showed a significant increase at 24 months.
Conclusion: Long BP (250 cm) OAGB in patients with BMI > 50 kg/m2 with TWL > 6 m had good results in the achievement of weight loss and weight maintenance goals with remission of associated comorbidities as HTN and DM.
Keywords: BMI > 50; Long biliopancreatic limb; One anastomosis gastric bypass; Total bowel length.
© 2022. The Author(s).
Conflict of interest statement
The authors declare no competing interests.
Figures





Comment in
-
One Anastomosis Gastric Bypass: Weight Loss Results Are Not a Function of the Biliary Limb Length!Obes Surg. 2022 Sep;32(9):3182. doi: 10.1007/s11695-022-06170-1. Epub 2022 Jun 21. Obes Surg. 2022. PMID: 35729445 No abstract available.
-
Reply to Letter to the Editor: Outcomes and Effects of 250-cm Biliopancreatic Limb One Anastomosis Gastric Bypass in Patients with BMI > 50 kg/m2 with Total Bowel Length > 6 m: a 2-Year Follow-Up.Obes Surg. 2022 Sep;32(9):3183-3184. doi: 10.1007/s11695-022-06171-0. Epub 2022 Jun 22. Obes Surg. 2022. PMID: 35729446 No abstract available.
Similar articles
-
Standard Biliopancreatic Limb (50 cm) Roux-en-Y Gastric Bypass Versus Long Biliopancreatic Limb (100 cm) Roux-en-Y Gastric Bypass in Patients with Body Mass Index 40-50 kg/m2: a Randomized Prospective Study.Obes Surg. 2022 Mar;32(3):577-586. doi: 10.1007/s11695-021-05868-y. Epub 2022 Jan 3. Obes Surg. 2022. PMID: 34981324 Clinical Trial.
-
One Anastomosis Gastric Bypass-Mini Gastric Bypass with Tailored Biliopancreatic Limb Length Formula Relative to Small Bowel Length: Preliminary Results.Obes Surg. 2019 Sep;29(9):3062-3070. doi: 10.1007/s11695-019-04019-8. Obes Surg. 2019. PMID: 31209832
-
MGB-OAGB: Effect of Biliopancreatic Limb Length on Nutritional Deficiency, Weight Loss, and Comorbidity Resolution.Obes Surg. 2018 Nov;28(11):3439-3445. doi: 10.1007/s11695-018-3405-7. Obes Surg. 2018. PMID: 30032419
-
One Anastomosis Gastric Bypass Versus Roux-en-Y Gastric Bypass for Obesity: a Systematic Review and Meta-Analysis of Randomized Clinical Trials.Obes Surg. 2020 Apr;30(4):1211-1218. doi: 10.1007/s11695-019-04288-3. Obes Surg. 2020. PMID: 31749109
-
Optimal Bilio-Pancreatic Limb (BPL) Length in One Anastomosis Gastric Bypass (OAGB) Surgery.Curr Obes Rep. 2025 Jan 25;14(1):14. doi: 10.1007/s13679-025-00608-0. Curr Obes Rep. 2025. PMID: 39862312 Review.
Cited by
-
The length of the biliopancreatic limb in one anastomosis gastric bypass.Front Surg. 2024 Aug 14;11:1248744. doi: 10.3389/fsurg.2024.1248744. eCollection 2024. Front Surg. 2024. PMID: 39220620 Free PMC article. Review.
-
One anastomosis gastric bypass as a one-stage bariatric surgical procedure in patients with BMI ≥ 50 kg/m2.Sci Rep. 2022 Jun 22;12(1):10507. doi: 10.1038/s41598-022-14485-3. Sci Rep. 2022. PMID: 35732861 Free PMC article.
-
Does One-Anastomosis Gastric Bypass Expose Patients to Gastroesophageal Reflux: a Systematic Review and Meta-analysis.Obes Surg. 2023 Dec;33(12):4080-4102. doi: 10.1007/s11695-023-06866-y. Epub 2023 Oct 25. Obes Surg. 2023. PMID: 37880462
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Research Materials