Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Observational Study
. 2022 Apr 29;22(1):169.
doi: 10.1186/s12890-022-01934-y.

Impact of anxiety and depression on the prognosis of copd exacerbations

Sandra Martínez-Gestoso  1 , María-Teresa García-Sanz  2 , José-Martín Carreira  3 , Francisco-Javier Salgado  4   5   6 , Uxío Calvo-Álvarez  7 , Liliana Doval-Oubiña  1 , Sandra Camba-Matos  1 , Lorena Peleteiro-Pedraza  8 , Miguel-Angel González-Pérez  9 , Pedro Penela-Penela  10 , Andrés Vilas-Iglesias  10 , Francisco-Javier González-Barcala  4   6   11   12
Affiliations
Observational Study

Impact of anxiety and depression on the prognosis of copd exacerbations

Sandra Martínez-Gestoso et al. BMC Pulm Med. .

Erratum in

  • Correction to: Impact of anxiety and depression on the prognosis of copd exacerbations.
    Martínez-Gestoso S, García-Sanz MT, Carreira JM, Salgado FJ, Calvo-Álvarez U, Doval-Oubiña L, Camba-Matos S, Peleteiro-Pedraza L, González-Pérez MA, Penela-Penela P, Vilas-Iglesias A, González-Barcala FJ. Martínez-Gestoso S, et al. BMC Pulm Med. 2022 May 30;22(1):213. doi: 10.1186/s12890-022-01999-9. BMC Pulm Med. 2022. PMID: 35637477 Free PMC article. No abstract available.

Abstract

Background: Frequent and highly prevalent as comorbidities in Chronic Obstructive Pulmonary Disease (COPD) patients, both depression and anxiety seem to have an impact on COPD prognosis. However, they are underdiagnosed and rarely treated properly.

Aim: To establish the prevalence of depression and anxiety in patients admitted for Acute Exacerbation of COPD (AECOPD) and determine their influence on COPD prognosis.

Methods: Prospective observational study conducted from October 1, 2016 to October 1, 2018 at the following centers in Galicia, Spain: Salnés County Hospital, Arquitecto Marcide, and Clinic Hospital Complex of Santiago de Compostela. Patients admitted for AECOPD who agreed to participate and completed the anxiety and depression scale (HADS) were included in the study.

Results: 288 patients (46.8%) were included, mean age was 73.7 years (SD 10.9), 84.7% were male. 67.7% patients were diagnosed with probable depression, and depression was established in 41.7%; anxiety was probable in 68.2% and established in 35.4%. 60.4% of all patients showed symptoms of both anxiety and depression. Multivariate analysis relates established depression with a higher risk of late readmission (OR 2.06, 95% CI 1.28; 3.31) and a lower risk of mortality at 18 months (OR 0.57, 95% CI 0.37; 0.90).

Conclusion: The prevalence of anxiety and depression in COPD patients is high. Depression seems to be an independent factor for AECOPD, so early detection and a multidisciplinary approach could improve the prognosis of both entities. The study was approved by the Ethical Committee of Galicia (code 2016/460).

Keywords: Anxiety; COPD; Depression; Prognosis.

PubMed Disclaimer

Conflict of interest statement

Gonzalez-Barcala Francisco-Javier has received speaker fees, consulting fees or research grants from ALK, Astra-Zeneca, Bial, Boehringer-Ingelheim, Chiesi, Gebro Pharma, GlaxoSmithKline, Laboratorios Esteve, Menarini, Mundipharma, Novartis, Rovi, Roxall, Sanofi, Stallergenes-Greer and Teva. The remaining authors declare that they have no competing interests.

References

    1. Miravitlles M, Calle M, Molina J, Almagro P, Gómez JT, Trigueros JA, Cosío BG, Casanova C, López-Campos JL, Riesco JA, Simonet P, Rigau D, Soriano JB, Ancochea J, Soler-Cataluña JJ. [Translated article] Spanish COPD guidelines (GesEPOC) 2021: Updated pharmacological treatment of stable COPD. Arch Bronconeumol. 2021;58(1):T69–81. 10.1016/j.arbres.2021.03.026 (English, Spanish). - PubMed
    1. De Miguel Díez J, Jiménez García R, López de Andrés A. Living with COPD: pain is important too. Arch Bronconeumol. 2020;56(6):351–352. doi: 10.1016/j.arbres.2019.08.005. - DOI - PubMed
    1. García-Sanz MT, González-Barcala FJ. COPD is more than just lung function: let's not forget depression. Arch Bronconeumol. 2021 doi: 10.1016/j.arbr.2021.05.023. - DOI - PubMed
    1. García-Sanz MT, Cánive-Gómez JC, Senín-Rial L, et al. One-year and long-term mortality in patients hospitalized for chronic obstructive pulmonary disease. J Thorac Dis. 2017;9(3):636–645. doi: 10.21037/jtd.2017.03.34. - DOI - PMC - PubMed
    1. Soler-Cataluña JJ, Miralles C. Exacerbation syndrome in COPD: a paradigm shift. Ach Bronconeumol. 2021;57:247–248. - PubMed

Publication types