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Review
. 2022 Sep;33(5):622-627.
doi: 10.1111/cyt.13134. Epub 2022 May 26.

Alveolar soft part sarcoma: A case report and review of the literature

Neha Singh  1 , Prajwala Gupta  1 , Sunayana Misra  1 , Arvind Ahuja  1 , Vijay Kumar Jain  2
Affiliations
Review

Alveolar soft part sarcoma: A case report and review of the literature

Neha Singh et al. Cytopathology. 2022 Sep.

Abstract

Alveolar soft part sarcoma (ASPS) is a rarely diagnosed tumour of deep soft tissue origin. This tumour is more common in adolescents and young adults and has a slowly progressive clinical course, which often leads to delayed diagnosis and treatment. It is highly vascular, can be confused with other entities like haemangiomas and arteriovenous malformations clinically and radiologically and is thus challenging to report on fine needle aspiration cytology (FNAC). Diagnosing the tumour is difficult on cytology, so knowledge of this entity and the differentials with its morphological mimics on cytology is required for timely diagnosis and early management of the patient. We report a case of ASPS in a young female who presented with a large, painless swelling in the thigh, diagnosed on cytology combined with ancillary testing with immunohistochemical markers.

Keywords: FNAC; alveolar soft part sarcoma (ASPS); immunohistochemical markers; soft tissue.

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References

REFERENCES

    1. Singh V, Bhargava M, Kumar V, Misra V. The untold story of primary alveolar soft part sarcoma of the fibula: a rare case report with review of the literature. Ind J Case Rep. 2020;6(04):209-211.
    1. Al Nakshabandi A, Daher A. Alveolar soft part sarcoma of hypopharynx; a case report. Ear, Nose Throat J. 2020;1-4. doi:10.1177/0145561320982164
    1. Carter JE, Evans TN, Tucker JA. Cytologic diagnosis of alveolar soft part sarcoma of the lower extremity by fine needle aspiration and correlation with core biopsy: a case report. Acta Cytol. 2008;52(4):459-463.
    1. Agarwal S, Gupta R, Iyer V, Mathur S, Ray R. Cytopathological diagnosis of alveolar soft part sarcoma, a rare soft tissue neoplasm. Cytopathology. 2010;22(5):318-322.
    1. Wakely P, McDermott J, Ali S. Cytopathology of alveolar soft part sarcoma: a report of 10 cases. Cancer Cytopathol. 2009;117(6):500-507.

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