Management of wounds treated by thrombin coagulation

Abstract

Thrombin solution was applied to skin-graft donor sites following skin removal with a Reese dermatome. Immediately after the blood was clotted by the thrombin solution, sheets of silicone gauze were applied to the clotting site. Forty-eight hours after the operation, the coagulated blood had disappeared spontaneously. In a total of 21 operations, the wounds treated by the above method healed completely without infection.