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Review
. 2022 May 1;4(1):11.
doi: 10.1186/s42836-022-00113-y.

Risk factors associated with surgical site infections following joint replacement surgery: a narrative review

Tao Li  1 , Haining Zhang  1 , Ping Keung Chan  2 , Wing Chiu Fung  3 , Henry Fu  3 , Kwong Yuen Chiu  3
Affiliations
Review

Risk factors associated with surgical site infections following joint replacement surgery: a narrative review

Tao Li et al. Arthroplasty. .

Abstract

Background: Surgical site infection following joint replacement surgery is still a significant complication, resulting in repeated surgery, prolonged antibiotic therapy, extended postoperative hospital stay, periprosthetic joint infection, and increased morbidity and mortality. This review discusses the risk factors associated with surgical site infection.

Related risk factors: The patient-related factors include sex, age, body mass index (BMI), obesity, nutritional status, comorbidities, primary diagnosis, living habits, and scores of the American Society of Anesthesiologists physical status classification system, etc. Surgery-related factors involve preoperative skin preparation, prolonged duration of surgery, one-stage bilateral joint replacement surgery, blood loss, glove changes, anti-microbial prophylaxis, topical anti-bacterial preparations, wound management, postoperative hematoma, etc. Those risk factors are detailed in the review.

Conclusion: Preventive measures must be taken from multiple perspectives to reduce the incidence of surgical site infection after joint replacement surgery.

Keywords: Joint replacement; Risk factor; Surgical site infection.

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Conflict of interest statement

The authors declare that they have no competing interests and they were not involved in the journal’s review of or decisions related to, this manuscript.

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References

    1. Gundtoft PH, Pedersen AB, Varnum C, Overgaard S. Increased mortality after prosthetic joint infection in primary THA. Clin Orthop Relat Res. 2017;475(11):2623–2631. doi: 10.1007/s11999-017-5289-6. - DOI - PMC - PubMed
    1. Kapadia BH, Berg RA, Daley JA, Fritz J, Bhave A, Mont MA. Periprosthetic joint infection. Lancet. 2016;387(10016):386–394. doi: 10.1016/S0140-6736(14)61798-0. - DOI - PubMed
    1. Del Pozo JL, Patel R. Clinical practice. Infection associated with prosthetic joints. N Engl J Med. 2009;361(8):787–94. doi: 10.1056/NEJMcp0905029. - DOI - PMC - PubMed
    1. Kurtz SM, Lau E, Watson H, Schmier JK, Parvizi J. Economic burden of periprosthetic joint infection in the United States. J Arthroplasty. 2012;27(8 Suppl):61–5.e1. doi: 10.1016/j.arth.2012.02.022. - DOI - PubMed
    1. Ridgeway S, Wilson J, Charlet A, Kafatos G, Pearson A, Coello R. Infection of the surgical site after arthroplasty of the hip. J Bone Joint Surg Br. 2005;87(6):844–850. doi: 10.1302/0301-620X.87B6.15121. - DOI - PubMed

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