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Comment
. 2022 Aug;85(2):174-211.
doi: 10.1016/j.jinf.2022.04.040. Epub 2022 Apr 29.

SARS-CoV-2 Omicron sublineage BA.2 replaces BA.1.1: Genomic surveillance in Japan from September 2021 to March 2022

Yosuke Hirotsu  1 , Makoto Maejima  2 , Masahiro Shibusawa  3 , Yume Natori  4 , Yuki Nagakubo  5 , Kazuhiro Hosaka  6 , Hitomi Sueki  7 , Hitoshi Mochizuki  8 , Toshiharu Tsutsui  9 , Yumiko Kakizaki  10 , Yoshihiro Miyashita  11 , Masao Omata  12
Affiliations
Comment

SARS-CoV-2 Omicron sublineage BA.2 replaces BA.1.1: Genomic surveillance in Japan from September 2021 to March 2022

Yosuke Hirotsu et al. J Infect. 2022 Aug.
No abstract available

Keywords: BA.2; Omicron, BA.1; SARS-CoV-2; Variant of concern.

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Conflict of interest statement

Declaration of Competing Interest None.

Figures

Fig 1
Fig. 1
Changes in Omicron strain prevalence SARS-CoV-2 strains identified from September 2021 to March 2022. Orange boxes indicate Delta strains, and blue boxes indicate Omicron strains. (B, C) Sublineage of Omicron strains detected from January 2022 to March 2022, indicated by BA.1 (pink), BA.1.1 (green), and BA.2 (blue). The number of samples detected per day (B) and the frequency of detection (C) are shown.
Fig 2
Fig. 2
Viral load and age of infected patients for sublineages BA.1. and BA.2. (A, B) The viral load and Ct values in Omicron sublineages BA.1.1 (n = 748) and BA.2 (n = 118) were analyzed by RT-qPCR. Box plots show the viral load (A) and Ct values (B) in BA.1.1 and BA.2. (C) Box plot shows the age of patients infected with sublineage BA.1.1 or BA.2. (D, E) Relationship between patient age and viral load (D) or Ct value (E). Pearson's correlation coefficient (r) is noted in the figures. The gray background of the regression line indicates the 95% confidence interval.
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Comment on

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