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. 2022 May-Jun;74(3):170-177.
doi: 10.1016/j.ihj.2022.04.008. Epub 2022 Apr 29.

Cardiac complications of COVID-19: Incidence and outcomes

Jayasree Pillarisetti  1 , Mubeen S Cheema  2 , Justin Haloot  2 , Manoj Panday  2 , Auroa Badin  2 , Anjlee Mehta  2 , Allen S Anderson  2 , Anand Prasad  2
Affiliations

Cardiac complications of COVID-19: Incidence and outcomes

Jayasree Pillarisetti et al. Indian Heart J. 2022 May-Jun.

Abstract

Background: Coronavirus disease-2019 (COVID-19) has been associated with pre-existing cardiac conditions as well as cardiovascular complications. The incidence rates of cardiac complications, age, and gender differences in this population are unknown.

Objectives: We wanted to study the incidence of cardiac complications and mortality in patients with COVID-19.

Methods: Data from the TriNetX COVID-19 global research network platform was used to identify COVID-19 patients. We compared patients with and without cardiac complications in patients with COVID-19 and obtained survival data.

Results: The final cohort was composed of 81,844 patients with COVID-19. Cardiac complications occurred in 9.3% of patients as follows: acute coronary syndromes in 1.3%, heart failure in 4.4%, atrial fibrillation in 4.5%, sinus bradycardia 1.9%, ventricular tachycardia in 0.5% and complete heart block in 0.01%. Mortality was significantly higher in patients with the cardiac complications mentioned (20%) than in those without them (2.9%) (odds ratio 7.2, 95% CI, 6.7-7.7; p < 0.0001). Older males seem to have higher incidence of cardiac complications and mortality.

Conclusions: Patients with COVID-19 who have cardiac complications have a higher risk of mortality when compared to those without cardiac complications.

Keywords: COVID-19; Cardiac complications; Mortality; SARS-CoV-2.

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Figures

Fig. 1
Fig. 1
Incidence of cardiac Complications of COVID-19.
Fig. 2
Fig. 2
a. New onset cardiac complications. b. Number of de novo events and total events (se novo and recurrent).
Fig. 3
Fig. 3
Number of Health Care Organizations from which data is obtained.
Fig. 4
Fig. 4
b. Propensity Matched Kaplan Meier survival curves for patients with and without cardiac complications.
See this image and copyright information in PMC

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