Targeted screening in the UK: A narrow concept with broad application
- PMID: 35492962
- PMCID: PMC9038565
- DOI: 10.1016/j.lanepe.2022.100353
Targeted screening in the UK: A narrow concept with broad application
Abstract
A recent report on screening in the UK proposed that the responsibility for recommendations on population and targeted screening programmes should be held by one new integrated advisory body. There is no wide international consensus on the definition of targeted screening. Our review identified and compared the defining components of screening terms: targeted, population, selective, and cascade screening, and case finding. Definitions of targeted screening and population screening were clearly demarcated by the eligible population; targeted and selective screening were found to be conceptually interchangeable; cascade screening, whilst conceptually similar to targeted screening across several components, was only used within the context of genetic diseases. There was little consensus between different definitions of case finding. These comparisons contributed to an updated definition of targeted screening. Considerable overlap between definition components across terms implies that a broad range of disease areas may fall into the remit of the new advisory body.
Keywords: Cascade screening; Case finding; Population screening; Screening; Selective screening; Targeted screening.
© 2022 The Author(s).
Conflict of interest statement
All authors have completed the ICMJE uniform disclosure form at www.icmje.org/coi_disclosure.pdf and declare: AB and MM have received grants from the UK NSC for the submitted work; FS, CV, AM, and JM are employed by the UK NSC; no other relationships or activities that could appear to have influenced the submitted work.
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