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. 2022 Mar 23;9(5):ofac152.
doi: 10.1093/ofid/ofac152. eCollection 2022 May.

High and Rapid Increase in Seroprevalence for SARS-CoV-2 in Conakry, Guinea: Results From 3 Successive Cross-Sectional Surveys (ANRS COV16-ARIACOV)

Abou Aissata Soumah  1 , Mamadou Saliou Kalifa Diallo  1   2 , Emilande Guichet  2 , David Maman  3 , Guillaume Thaurignac  2 , Alpha Kabinet Keita  1   2 , Julie Bouillin  2 , Haby Diallo  1 , Raphael Pelloquin  2 , Ahidjo Ayouba  2 , Cece Kpamou  1 , Martine Peeters  2 , Eric Delaporte  2 , Jean-Francois Etard  2 , Abdoulaye Toure  1
Affiliations

High and Rapid Increase in Seroprevalence for SARS-CoV-2 in Conakry, Guinea: Results From 3 Successive Cross-Sectional Surveys (ANRS COV16-ARIACOV)

Abou Aissata Soumah et al. Open Forum Infect Dis. .

Abstract

We conducted 3 successive seroprevalence surveys, 3 months apart, using multistage cluster sampling to measure the extent and dynamics of the severe acute respiratory syndrome coronavirus 2 epidemic in Conakry, the capital city of Guinea. Seroprevalence increased from 17.3% (95% CI, 12.4%-23.8%) in December 2020 during the first survey (S1) to 28.9% (95% CI, 25.6%-32.4%) in March/April 2021 (S2), then to 42.4% (95% CI, 39.5%-45.3%) in June 2021 (S3). This significant overall trend of increasing seroprevalence (P < .0001) was also significant in every age class, illustrating a sustained transmission within the whole community. These data may contribute to defining cost-effective response strategies.

Keywords: COVID-19; Guinea; SARS-CoV-2; population-based survey; seroprevalence.

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Figures

Figure 1.
Figure 1.
Age-standardized seroprevalence of SARS-CoV-2 in 3 consecutive population based surveys at 3 months interval in Conakry, Guinea. The graphs show the prevalence of SARS-CoV-2 IgG antibodies per age category and total for survey 1 (blue), survey 2 (red), survey 3 (green). Dots represent the estimated prevalence and bars represent 95% CIs. Abbreviations: IgG, immunoglobulin G; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
See this image and copyright information in PMC

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