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Comparative Study
. 1987 Mar 15;43(3):323-4.
doi: 10.1007/BF01945569.

Insulin-like effect of dichloroacetic acid on hexose transport in Swiss 3T3 cells

K Kitagawa, H Nishino, A Iwashima
Comparative Study

Insulin-like effect of dichloroacetic acid on hexose transport in Swiss 3T3 cells

K Kitagawa et al. Experientia. .

Abstract

Hexose transport in Swiss 3T3 cells was increased by treatment with dichloroacetic acid as well as by treatment with insulin. Neither extra- nor intracellular Ca2+ was found to be involved in their stimulatory action. On the other hand, the removal of intracellular Mg2+ resulted in a loss of the stimulation. These results suggest that dichloroacetic acid stimulates the hexose transport in Mg2+-dependent manner, similar to that of insulin.

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