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. 2022 Jan 21;9(3):174-178.
doi: 10.1016/j.apjon.2022.01.003. eCollection 2022 Mar.

The relationship between work-related outcomes and symptoms in early breast cancer survivors receiving adjuvant endocrine therapy

Mayumi Nakao  1 , Hiroko Komatsu  2 , Tetsu Hayashida  3 , Maiko Takahashi  4 , Tomoko Seki  3 , Kaori Yagasaki  5
Affiliations

The relationship between work-related outcomes and symptoms in early breast cancer survivors receiving adjuvant endocrine therapy

Mayumi Nakao et al. Asia Pac J Oncol Nurs. .

Abstract

Objective: This study examined the relationship between symptom burdens and work-related outcomes, including work participation and overall work impairment (OWI) among breast cancer survivors (BCS) receiving adjuvant endocrine therapy (AET).

Methods: This was a cross-sectional study with 140 BCS of working age receiving AET. Data were collected using self-report questionnaires that included an assessment of symptoms and their employment status, and OWI. Data were analyzed using descriptive statistics and multiple logistic regression analysis.

Results: A total of 111 (79%) survivors reported being employed at the time of the survey. Symptom burdens were not associated with unemployment. Of the 110 working BCS receiving AET, symptom burdens were significantly related to a higher degree of OWI (OR ​= ​2.14, 95% CI, 1.58-2.89, P ​≤ ​0.001).

Conclusions: Participating BCS receiving AET continued to work while experiencing symptoms, with survivors who experienced high symptom burdens being negatively affected in their work life. Healthcare providers need to assess and manage symptoms and their impact on work, with the help of employers, to improve the quality of work life of BCS receiving AET.

Keywords: Breast cancer survivors; Endocrine therapy; Symptoms; Work.

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References

    1. Cancer Today. Estimated number of new cases in 2020, worldwide, both sexes, all ages. International agency of research on cancer. WHO. https://gco.iarc.fr/today/online-analysis-table?v=2020&mode=cancer&mode_.... Accessed 3 Jan 2021.
    1. Burstein H.J., Temin S., Anderson H., Buchholz T.A., Davidson N.E., Gelmon K.E., et al. Adjuvant endocrine therapy for women with hormone receptor-positive breast cancer: American Society of Clinical Oncology clinical practice guideline focused update. J Clin Oncol. 2014;32:2255–2269. - PMC - PubMed
    1. Ganz P.A., Petersen L., Bower J.E., Crespi C.M. Impact of adjuvant endocrine therapy on quality of life and symptoms: observational data over 12 months from the Mind-Body Study. J Clin Oncol. 2016;34:816–824. - PMC - PubMed
    1. Zhu Y., Cohen S.M., Rosenzweig M.Q., Bender C.M. Symptom map of endocrine therapy for breast cancer: a scoping review. Cancer Nurs. 2019;42:E19–E30. - PMC - PubMed
    1. van Londen G.J., Beckjord E.B., Dew M.A., Cooper K.L., Davidson N.E., Bovbjerg D.H., et al. Associations between adjuvant endocrine therapy and onset of physical and emotional concerns among breast cancer survivors. Support Care Cancer. 2014;22:937–945. - PMC - PubMed

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