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. 2022 Apr 13:10:837462.
doi: 10.3389/fped.2022.837462. eCollection 2022.

Pediatric Intestinal Pseudo-Obstruction: Progress and Challenges

Marie-Catherine Turcotte  1 , Christophe Faure  1
Affiliations

Pediatric Intestinal Pseudo-Obstruction: Progress and Challenges

Marie-Catherine Turcotte et al. Front Pediatr. .

Abstract

Background: Chronic intestinal pseudo-obstruction is a rare disorder and represents the most severe form of gastrointestinal dysmotility with significant morbidity and mortality. Emerging research shows considerable differences between the adult and pediatric population with intestinal pseudo-obstruction and the term Pediatric Intestinal Pseudo-Obstruction (PIPO) was recently proposed.

Purpose: The aim of this article is to provide pediatric gastroenterologists and pediatricians with an up to date review of the etiology and underlining pathophysiology, clinical features, diagnostic and management approaches currently available for PIPO and to discuss future perspectives for the diagnosis and management of this rare disease.

Keywords: Pediatric Intestinal Pseudo-Obstruction; antroduodenal manometry; autoimmune GI dysmotility; intestinal transplantation; myopathy; neuropathy.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The handing editor TO declared a past co-authorship with CF.

Figures

FIGURE 1
FIGURE 1
Algorithm for diagnosis and management of Pediatric Intestinal Pseudo-Obstruction.
See this image and copyright information in PMC

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