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. 2022 Jan-Dec:29:10732748221099227.
doi: 10.1177/10732748221099227.

Recent Estimates and Predictions of 5-Year Survival in Patients with Gastric Cancer: A Model-Based Period Analysis

Yunmei Li  1   2 , Aozi Feng  1 , Shuai Zheng  3 , Chong Chen  3 , Jun Lyu  1
Affiliations

Recent Estimates and Predictions of 5-Year Survival in Patients with Gastric Cancer: A Model-Based Period Analysis

Yunmei Li et al. Cancer Control. 2022 Jan-Dec.

Abstract

Background: The overall incidence and mortality of gastric cancer have steadily declined in the United States over the past few decades, but it is still a serious disease burden for patients. Therefore, it is of great significance to evaluate the latest survival rate of gastric cancer.

Methods: Based on the Surveillance, Epidemiology, and End Results database, this study analyzed the age-standardized relative survival rates and survival trends of gastric cancer cases in 2007-2011 and 2012-2016 using period analysis, and the survival rate 2017-2021 was predicted using a generalized linear model based on the period analysis.

Results: During 2007-2016, the 5-year relative survival rate of patients with gastric cancer continued to rise, and the same trend was observed in 2017-2021. The 5-year overall age-standardized relative survival rates in 2007-2011, 2012-2016, and 2017-2021 were 38.3%, 40.6%, and 42.9%, respectively. However, despite these favorable trends, the overall relative survival of patients with gastric cancer remains at a low level. There were significant differences in the relative survival rates of patients with gastric cancer in terms of age, sex, race, primary site, stage, and socioeconomic status. Notably, the survival rate of patients with distant-stage gastric cancer remains very low (10%).

Conclusion: We found that the survival rate of patients with gastric cancer showed different degrees of improvement in each subgroup. However, the overall relative survival rate of patients with gastric cancer remains low. Analyzing the changes of patients with gastric cancer in the last 10 years will be helpful in predicting the changing trend of cancer in the future. It also provides a scientific basis for relevant departments to formulate effective tumor prevention and control measures.

Keywords: gastric cancer; period analysis; prediction; surveillance, epidemiology, and end results; survival rate.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Flowchart of sample selection.
Figure 2.
Figure 2.
Trends of 5-year relative survival rate of all gastric cancer patients and between different sexes.
Figure 3.
Figure 3.
Trends of age-specific 5-year relative survival rate in patients with gastric cancer.
Figure 4.
Figure 4.
Trends of 5-year relative survival rate in patients with gastric cancer of different races.
Figure 5.
Figure 5.
Trends of 5-year relative survival rate in patients with gastric cancer of different races.
Figure 6.
Figure 6.
Trends of 5-year relative survival rate in patients with gastric cancer of different primary sites.
Figure 7.
Figure 7.
Trends of 5-year relative survival rate in patients with gastric cancer of different stages.
See this image and copyright information in PMC

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