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. 2022 Jun;40(6):1513-1522.
doi: 10.1007/s00345-022-03997-2. Epub 2022 May 2.

Global experience and progress in GreenLight-XPS 180-Watt photoselective vaporization of the prostate

Isabel Lichy  1 , Kyle Law  2 , Côme Tholomier  3 , David-Dan Nguyen  4 , Iman Sadri  3 , David Bouhadana  4 , Félix Couture  2 , Ahmed S Zakaria  5 , Naeem Bhojani  2 , Kevin C Zorn  2 , Franck Bruyère  6 , Luca Cindolo  7 , Giovanni Ferrari  7 , Carlos Vasquez-Lastra  8 , Tiago J Borelli-Bovo  9 , Edgardo F Becher  10 , Vincent Misrai  11 , Dean Elterman  12 , Maximilian Reimann #  13 , Hannes Cash #  14   15   16
Affiliations

Global experience and progress in GreenLight-XPS 180-Watt photoselective vaporization of the prostate

Isabel Lichy et al. World J Urol. 2022 Jun.

Abstract

Purpose: To evaluate changes in global perioperative data of GreenLight-XPS 180-Watt photo-selective vaporization of the prostate (GL-XPS) of the Global Greenlight Group (GGG) database.

Methods: 3441 men, who underwent GL-XPS for symptomatic BPH between 2011 and 2019 at seven high volume international centers, were included. Primary outcome measurements were operative time (OT; min), effective laser time (LT; min of OT), as well as intraoperative and postoperative adverse events (AEs), all analyzed by year of surgery (2011-2019) and prostate volume (PV) group (< 80 ml vs. 80-150 ml vs. > 150 ml).

Results: The median age was 70 years (interquartile range 64-77), the median PV was 64 ml (IQR 47-90). The OT and LT slightly increased but stayed highly efficient all in all. Median OT was 60 min (IQR 45-83) and LT was 33 min (IQR 23-46). Median energy use was 253 kJ (IQR 170-375) with an energy density of 3.94 kJ/ml (IQR 2.94-5.02). The relative probability of perioperative AEs decreased by 17% each year (p < 0.001). The relative probability of perioperative transfusion dropped significantly from 2% in 2011 to 0% in 2019 (p = 0.007). The early postoperative complications (within 30 days after surgery) decreased significantly from 48.8% (n = 106) in 2011 to 24.7% (n = 20) in 2019 (p > 0.001).

Conclusion: These findings from the GGG demonstrate significant improvement secondary to growing experience with GL-XPS between 2011 and 2019 in intraoperative AEs, including transfusions, and postoperative AEs. While staying highly efficient in OT and LT of GL-XPS within a 9-year period of experience.

Keywords: BPH; GL-XPS; Global Greenlight Group; Global experience; Greenlight.

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Conflict of interest statement

Hannes Cash, Kevin Zorn, Dean Elterman, Edgardo F. Becher, Giovanni Ferrari and Luca Cindolo report receiving honoraria as consultant/proctor for Boston Scientific. All other authors report no conflict of interest.

Figures

Fig. 1
Fig. 1
Clinical research flowchart
Fig. 2
Fig. 2
Significant parameters of intraoperative baseline results between 2011 and 2019 in correlation to prostate volume group 1–3, a OT, b LT, c LT/OT ratio, d LT/TRUS volume, e Energy/LT, f Energy used, g complications, perioperative
Fig. 3
Fig. 3
Early postoperative complications (< 30 days) between 2011 and 2019 in correlation to prostate volume group 1–3
See this image and copyright information in PMC

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