Meta-Analysis

. 2022 Jun;24(6):1139-1141.

doi: 10.1002/ejhf.2531. Epub 2022 May 16.

Insulin resistance and incident heart failure: a meta-analysis

Sebhat Erqou¹, Amanda I Adler², Azariyas A Challa³, Gregg C Fonarow⁴, Justin B Echouffo-Tcheugui⁵

Affiliations

¹ Division of Cardiovascular Medicine, Department of Medicine, Providence VA Medical Center and Alpert Medical School of Brown University, Providence, RI, USA.
² Diabetes Trials Unit, University of Oxford, Oxford, UK.
³ Division of Cardiovascular Medicine, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
⁴ Ahmanson-UCLA Cardiomyopathy Center, Ronald Reagan UCLA Medical Center, Los Angeles, CA, USA.
⁵ Division of Endocrinology, Diabetes & Metabolism, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.

PMID: 35502564
PMCID: PMC9262840
DOI: 10.1002/ejhf.2531

Meta-Analysis

Insulin resistance and incident heart failure: a meta-analysis

Sebhat Erqou et al. Eur J Heart Fail. 2022 Jun.

. 2022 Jun;24(6):1139-1141.

doi: 10.1002/ejhf.2531. Epub 2022 May 16.

Authors

Sebhat Erqou¹, Amanda I Adler², Azariyas A Challa³, Gregg C Fonarow⁴, Justin B Echouffo-Tcheugui⁵

Affiliations

¹ Division of Cardiovascular Medicine, Department of Medicine, Providence VA Medical Center and Alpert Medical School of Brown University, Providence, RI, USA.
² Diabetes Trials Unit, University of Oxford, Oxford, UK.
³ Division of Cardiovascular Medicine, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
⁴ Ahmanson-UCLA Cardiomyopathy Center, Ronald Reagan UCLA Medical Center, Los Angeles, CA, USA.
⁵ Division of Endocrinology, Diabetes & Metabolism, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.

PMID: 35502564
PMCID: PMC9262840
DOI: 10.1002/ejhf.2531

No abstract available

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Figures

**Figure 1**
Overall relative risk (RR) (95% confidence interval [CI]) of incident heart failure associated with insulin resistance for: comparison of the top versus bottom tertiles of the distribution of the homeostasis model assessment for insulin resistance (HOMA‐IR) index. (A) Minimally adjusted (unadjusted or age‐ and sex‐adjusted) RR. (B) Maximally adjusted RR. Each standard deviation (SD) change in HOMA‐IR index. (C) Minimally adjusted (unadjusted or age‐ and sex‐adjusted) RR. (D) Maximally adjusted RR.

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References

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Insulin resistance and incident heart failure: a meta-analysis

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