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. 2022 Mar 10;4(2):e220019.
doi: 10.1148/ryct.220019. eCollection 2022 Apr.

Imaging of Myocarditis Following mRNA COVID-19 Booster Vaccination

Felipe Sanchez Tijmes  1 , Anibal Zamorano  1 , Paaladinesh Thavendiranathan  1 , Kate Hanneman  1
Affiliations

Imaging of Myocarditis Following mRNA COVID-19 Booster Vaccination

Felipe Sanchez Tijmes et al. Radiol Cardiothorac Imaging. .

Abstract

Keywords: Echocardiography, MR-Functional Imaging, MRI, Cardiac Supplemental material is available for this article.

Keywords: Cardiac; Echocardiography; MR-Functional Imaging; MRI.

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Conflict of interest statement

Disclosures of conflicts of interest: F.S.T. No relevant relationships. A.Z. No relevant relationships. P.T. Speaker’s honorarium from Amgen, Boehringer Ingelheim-Lilly, and Takeda. K.H. Speaker’s honorarium from Sanofi-Genzyme, Amicus and Medscape; associate editor of Radiology: Cardiothoracic Imaging.

Figures

Basal short-axis 1.5-T cardiac MR images demonstrate (A) subepicardial late gadolinium enhancement at the basal inferior and inferior lateral wall (red arrows), with corresponding (B) hyperintensity on T2-weighted image (orange arrows), (C) abnormal high regional native T1 (1123 msec, blue arrows [upper reference range, 960 msec]), and (D) abnormal high regional T2 (58 msec, green arrows [upper reference range, 51 msec]). These findings are in keeping with acute myocarditis based on the revised Lake Louise criteria. Global systolic function was impaired (left ventricular ejection fraction, 48%), with hypokinesis of the basal inferolateral wall. (E) Speckle-tracking echocardiography–based global longitudinal strain demonstrates reduced strain involving most basal segments (global longitudinal strain, −18%).
Basal short-axis 1.5-T cardiac MR images demonstrate (A) subepicardial late gadolinium enhancement at the basal inferior and inferior lateral wall (red arrows), with corresponding (B) hyperintensity on T2-weighted image (orange arrows), (C) abnormal high regional native T1 (1123 msec, blue arrows [upper reference range, 960 msec]), and (D) abnormal high regional T2 (58 msec, green arrows [upper reference range, 51 msec]). These findings are in keeping with acute myocarditis based on the revised Lake Louise criteria. Global systolic function was impaired (left ventricular ejection fraction, 48%), with hypokinesis of the basal inferolateral wall. (E) Speckle-tracking echocardiography–based global longitudinal strain demonstrates reduced strain involving most basal segments (global longitudinal strain, −18%).
See this image and copyright information in PMC

References

    1. Sanchez Tijmes F , Thavendiranathan P , Udell JA , Seidman MA , Hanneman K . Cardiac MRI Assessment of Nonischemic Myocardial Inflammation: State of the Art Review and Update on Myocarditis Associated with COVID-19 Vaccination . Radiol Cardiothorac Imaging 2021. ; 3 ( 6 ): e210252 . - PMC - PubMed
    1. Fronza M , Thavendiranathan P , Chan V , et al. . Myocardial Injury Pattern at MRI in COVID-19 Vaccine-associated Myocarditis . Radiology 2022. . 10.1148/radiol.212559. Published online February 15, 2022. - DOI - PMC - PubMed
    1. National Advisory Committee on Immunization. An Advisory Committee Statement (ACS) . Guidance on booster COVID-19 vaccine doses in Canada. https://www.canada.ca/content/dam/phac-aspc/documents/services/immunizat.... Updated December 3, 2021. Accessed February 1, 2022.

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