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Case Reports
. 2022 Feb 10;35(3):350-351.
doi: 10.1080/08998280.2022.2035163. eCollection 2022.

Histoplasmosis presenting as colitis and blood dyscrasias in a patient with systemic lupus erythematosus

Dua Noor Butt  1 , Muhamad Sheharyar Warraich  2 , Akshay Machanahalli Balakrishna  1 , Mahmoud Ismayl  1 , Sumbul Liaqat  3 , Kanza Noor Butt  4 , Joseph Thirumalareddy  5 , Manasa Velagapudi  6
Affiliations
Case Reports

Histoplasmosis presenting as colitis and blood dyscrasias in a patient with systemic lupus erythematosus

Dua Noor Butt et al. Proc (Bayl Univ Med Cent). .

Abstract

A 28-year-old woman with a history of systemic lupus erythematosus on hydroxychloroquine and steroid therapy presented with fever, dysentery, and thrombocytopenia. Marrow aspirate revealed yeast forms of histoplasmosis. She was treated with liposomal amphotericin B followed by itraconazole with resolution of symptoms and marrow recovery.

Keywords: Anemia; colitis; histoplasmosis; thrombocytopenia.

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Figures

Figure 1.
Figure 1.
Budding yeast forms of Histoplasma on bone marrow biopsy.
See this image and copyright information in PMC

References

    1. Sane SY, Patel MG, Patel BM, Kokal K.. Disseminated histoplasmosis (a case report). J Postgrad Med. 1983;29(4):270–273. - PubMed
    1. Chu JH, Feudtner C, Heydon K, Walsh TJ, Zaoutis TE.. Hospitalizations for endemic mycoses: a population-based national study. Clin Infect Dis. 2006;42(6):822–825. doi:10.1086/500405 - DOI - PubMed
    1. Sathapatayavongs B, Batteiger BE, Wheat J, Slama TG, Wass JL.. Clinical and laboratory features of disseminated histoplasmosis during two large urban outbreaks. Medicine (Baltimore). 1983;62(5):263–270. doi:10.1097/00005792-198309000-00001. - DOI - PubMed
    1. Kauffman CA. Histoplasmosis: a clinical and laboratory update. Clin Microbiol Rev. 2007;20(1):115–132. doi:10.1128/CMR.00027-06. - DOI - PMC - PubMed
    1. Goodwin RA Jr, Shapiro JL, Thurman GH, Thurman SS, Des Prez RM.. Disseminated histoplasmosis: clinical and pathologic correlations. Medicine (Baltimore). 1980;59(1):1–33. doi:10.1097/00005792-198001000-00001. - DOI - PubMed

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