Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Mar 17;35(3):363-365.
doi: 10.1080/08998280.2022.2039496. eCollection 2022.

Cardiomyopathy and heart failure secondary to anabolic-androgen steroid abuse

Affiliations
Case Reports

Cardiomyopathy and heart failure secondary to anabolic-androgen steroid abuse

Onyedika J Ilonze et al. Proc (Bayl Univ Med Cent). .

Abstract

Bodybuilders often use anabolic-androgenic steroids to improve performance. We report a case of a 30-year-old male bodybuilder with anabolic-androgen steroid abuse while getting ready for a bodybuilding contest. He had New York Heart Association class IV heart failure, severe nonischemic dilated cardiomyopathy, new-onset atrial fibrillation, cardiogenic pulmonary edema, and acute respiratory distress requiring mechanical ventilation. After 6 months of heart failure guideline-directed medical therapy, cessation of anabolic steroids, and maintenance of sinus rhythm, his ejection fraction improved.

Keywords: Anabolic-androgen steroid; guideline-directed medical therapy; heart failure; nonischemic cardiomyopathy.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
(a) Electrocardiogram showing atrial flutter with 2:1 atrioventricular conduction. (b) Echocardiogram, parasternal long axis view, showing moderately dilated left ventricle and left atrium.

Similar articles

Cited by

References

    1. Baggish AL, Weiner RB, Kanayama G, et al. . Cardiovascular toxicity of illicit anabolic-androgenic steroid use. Circulation. 2017;135:1991–2002. doi:10.1161/CIRCULATIONAHA.116.026945. - DOI - PMC - PubMed
    1. Dickerman RD, Schaller F, McConathy WJ.. Left ventricular wall thickening does occur in elite power athletes with or without anabolic steroid use. Cardiology. 1998;90:145–148. doi:10.1159/000006834. - DOI - PubMed
    1. Frankenfeld SP, Oliveira LP, Ortenzi VH, et al. . The anabolic androgenic steroid nandrolone decanoate disrupts redox homeostasis in liver, heart and kidney of male Wistar rats. PLoS One. 2014;9:e102699. doi:10.1371/journal.pone.0102699. - DOI - PMC - PubMed
    1. Han HC, Farouque O, Hare DL.. Steroid-induced cardiomyopathy. Med J Aust. 2015;203:226–227e1. doi:10.5694/mja14.01491. - DOI - PubMed
    1. Montisci M, El Mazloum R, Cecchetto G, et al. . Anabolic androgenic steroids abuse and cardiac death in athletes: morphological and toxicological findings in four fatal cases. Forensic Sci Int. 2012;217:e13–e18. doi:10.1016/j.forsciint.2011.10.032. - DOI - PubMed

Publication types

LinkOut - more resources