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Review
. 2020 Sep 16;10(56):34308-34322.
doi: 10.1039/d0ra05692h. eCollection 2020 Sep 10.

Application status and technical analysis of chitosan-based medical dressings: a review

Shanguo Zhang  1   2 , Jianyong Li  1   2 , Jianfeng Li  1   2 , Na Du  3 , Donghai Li  4 , Fangyi Li  1   2 , Jia Man  1   2
Affiliations
Review

Application status and technical analysis of chitosan-based medical dressings: a review

Shanguo Zhang et al. RSC Adv. .

Abstract

Chitosan has wide applications in the field of medical dressings due to its good biomedical properties. This review provides the application status and technical analysis of chitosan medical dressings. First, we introduce the source and chemical structure of chitosan. Then, we investigate the mechanism of chitosan showing different medical properties. We also show the application of supramolecular chitosan-based hydrogels in the dressing field and the formulation optimization and the preparation technology of chitosan dressings for fabricating chitosan-based dressings with various morphologies and medical functions. After that, we introduce the research process of the modification method of chitosan dressings including single modification, blending modification, crosslinking modification, etc. Finally, based on the study of the medical effects of chitosan dressings, we analyze the existing problems in the preparation process and propose corresponding solutions from the aspects of the morphology, clinical feedback effect, and future development trends. This paper can provide a reference for further studies of skin tissue engineering and the development of new chitosan medical dressings.

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Conflict of interest statement

On behalf of all authors, the corresponding author declares no conflicts of interest.

Figures

Fig. 1
Fig. 1. Chemical structure of chitin and chitosan.
Fig. 2
Fig. 2. Theory of chitosan medical properties.
Fig. 3
Fig. 3. The preparation technology of chitosan dressing.
Fig. 4
Fig. 4. Preparation process of chitosan-based dressing by immersion precipitation phase inversion method.
Fig. 5
Fig. 5. Research framework for modification of chitosan dressing.
See this image and copyright information in PMC

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