Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Mar;26(3):381-383.
doi: 10.5005/jp-journals-10071-24131.

Emphysematous Liver Abscess and Disseminated Hypervirulent Klebsiella pneumoniae Infection in a Patient from Southern India

Affiliations
Case Reports

Emphysematous Liver Abscess and Disseminated Hypervirulent Klebsiella pneumoniae Infection in a Patient from Southern India

Amiya R Nayak et al. Indian J Crit Care Med. 2022 Mar.

Abstract

The pyogenic liver abscess is usually polymicrobial and is seen as a complication of biliary disease or peritonitis. Over the past three decades, monomicrobial liver abscess caused by Klebsiella pneumoniae is being increasingly reported from South East Asian countries like Taiwan and Korea. It is a community-acquired infection caused by a distinct strain, hypervirulent K. pneumoniae, different from classical strain related to the healthcare-associated Klebsiella infections. Diabetes mellitus is a significant risk factor. Reports of the disseminated infection due to hypervirulent Klebsiella are very few in Indian literature. We report the successful management of a diabetic patient with emphysematous liver abscess, brain abscess, and meningitis caused by hypervirulent K. pneumoniae infection.

How to cite this article: Nayak AR, Ramadoss R, Ramanathan V, Honnarudraiah NK. Emphysematous Liver Abscess and Disseminated Hypervirulent Klebsiella pneumoniae Infection in a Patient from Southern India. Indian J Crit Care Med 2022;26(3):381-383.

Keywords: Brain abscess; India; Klebsiella; Liver abscess.

PubMed Disclaimer

Conflict of interest statement

Source of support: Nil Conflict of interest: None

Figures

Figs 1A and B
Figs 1A and B
(A) CT scan of the abdomen showing irregular hypodense lesion with multiple air foci in segment 5 and 8 of the right lobe; (B) CT scan of the brain showing a hypodense lesion in the region of the left caudate nucleus and anterior limb of the left internal capsule
Figs 2A and B
Figs 2A and B
(A) CT scan of the abdomen shows a decrease in the size of the abscess and disappearance of air pockets; (B) CT scan of the brain shows partial resolution of brain abscess

References

    1. Podschun R, Ullmann U. Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors. Clin Microbiol Rev. 1998;11(4):589–603. doi: 10.1128/CMR.11.4.589. - DOI - PMC - PubMed
    1. Jun JB. Klebsiella pneumoniae liver abscess. Infect Chemother. 2018;50(3):210–218. doi: 10.3947/ic.2018.50.3.210. - DOI - PMC - PubMed
    1. Shah MY, Vij AS, Shah F, Seth S, Pandit NA. Amoebic liver abscess with metastatic amoebic brain abscess: a case report. Ann Trop Med Public Health. 2016;9(1):76–79. doi: 10.4103/1755-6783.174724. - DOI
    1. Kinsley JD, Nisheeth TP, Francis G, Srinivas CN. Aberrant form of Klebsiella pneumoniae in fulminant emphysematous hepatitis with polymicrobial infection. Era's Journal of Medical Research. 2017;4(1):35–37. doi: 10.24041/ejmr2017.6. - DOI
    1. Serraino C, Elia C, Bracco C, Rinaldi G, Pomero F, Silvestri A, et al. Characteristics and management of pyogenic liver abscess: a European experience. Medicine (Baltimore) 2018;97(19):e0628. doi: 10.1097/MD.0000000000010628. - DOI - PMC - PubMed

Publication types

LinkOut - more resources