Probiotics: Should We Use Them Proactively in Critical Illness?

Affiliations

Editorial

Kapil Dev Soni. Indian J Crit Care Med. 2022 Mar.

. 2022 Mar;26(3):266-267.

doi: 10.5005/jp-journals-10071-24174.

¹ Department of Critical and Intensive Care, JPN Apex Trauma Centre, All India Institute of Medical Sciences, New Delhi, India.

Abstract

Soni KD. Probiotics: Should We Use Them Proactively in Critical Illness? Indian J Crit Care Med 2022;26(3):266-267.

Keywords: Critical illness; Dysbiosis; Intensive care units; Probiotics; Systematic review; Umbrella review; Ventilator-associated pneumonia.

Source of support: Nil Conflict of interest: None

1. Pirracchio R, Gropper MA. Heterogeneity in intensive care: low severity does not mean low risk! Anesthesiology. 2019;130(2):190–191. doi: 10.1097/ALN.0000000000002537. - DOI - PubMed
1. Santacruz CA, Pereira AJ, Celis E, Vincent J-L. Which multicenter randomized controlled trials in critical care medicine have shown reduced mortality? A systematic review. Crit Care Med. 2019;47(12):1680–1691. doi: 10.1097/CCM.0000000000004000. - DOI - PubMed
1. Wischmeyer PE, McDonald D, Knight R. Role of the microbiome, probiotics, and “dysbiosis therapy” in critical illness. Curr Opin Crit Care. 2016;22(4):347–353. doi: 10.1097/MCC.0000000000000321. - DOI - PMC - PubMed
1. Batra P, Soni KD, Mathur P. Efficacy of probiotics in the prevention of VAP in critically ill ICU patients: an updated systematic review and meta-analysis of randomized control trials. J Intensive Care. 2020;8:81. doi: 10.1186/s40560-020-00487-8. - DOI - PMC - PubMed
1. Madsen K. Probiotics in critically ill patients. J Clin Gastroenterol. 2008;42((Suppl 3)):S116–S118. doi: 10.1097/MCG.0b013e31817283cb. Pt 1: - DOI - PubMed