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Observational Study
. 2022 Jun;35(5):1497-1503.
doi: 10.1007/s40620-022-01329-6. Epub 2022 May 6.

Influence of peritoneal dialysis catheter type on dislocations and laxative use: a retrospective observational study

Gianmarco Sabiu  1   2 , Marco Heidempergher  1 , Cristina De Salvo  1   2 , Maria Antonietta Orani  1 , Chiara Tricella  1   2 , Maurizio Gallieni  3   4   5
Affiliations
Observational Study

Influence of peritoneal dialysis catheter type on dislocations and laxative use: a retrospective observational study

Gianmarco Sabiu et al. J Nephrol. 2022 Jun.

Abstract

Background: There is currently no consensus regarding the optimal type of peritoneal dialysis (PD) catheter. Although few studies showed that weighted catheters result in lower complication rates and superior long-term outcomes than non-weighted catheters, there are no studies on the use of laxatives linked to catheter malfunction, a patient-related outcome potentially affecting the quality of life. Thus, we compared the burden of acute and chronic laxative use in a cohort of PD patients having either weighted or non-weighted catheters.

Methods: We performed a single-center, retrospective, observational study in two renal units, comparing acute and chronic laxative therapy related to catheter drainage failure in a cohort of 74 PD patient,s divided by peritoneal dialysis catheter type. In addition, we evaluated the number of patients who experienced minor and major dislocations, catheter-related infection rate, hospitalization for catheter malfunctioning, episodes of catheter repositioning, and dropout from PD.

Results: Laxative use was significantly more common among patients in the non-weighted catheter group (acute: 30.3% vs. 9.8%, p = 0.03; chronic: 36.4% vs. 12.2%; p≤0.02). Furthermore, weighted catheters were superior to non-weighted catheters for all the secondary outcomes (dislocations: 12.2% vs. 45.5%; p = 0.001).

Conclusions: Weighted self-locating catheters have lower drainage failure, thus reducing the need and burden of acute and chronic laxative use among PD patients.

Keywords: Drug burden; Laxative; Peritoneal catheter; Peritoneal dialysis.

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Conflict of interest statement

MG's institution, the University of Milano, received consulting fees from B. Braun Avitum Italy, the company manufacturing the weighted catheter. The other authors have nothing to disclose.

Figures

Fig. 1
Fig. 1
Patients selection and eligibility
Fig. 2
Fig. 2
Drainage failure management flowchart. Catheter repositioning, as well as the acute laxative use, increase the risk of catheter-related infections
See this image and copyright information in PMC

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