Hypoxia and Hypercoagulability in COVID-19: Chicken or the Egg?
- PMID: 35522846
- PMCID: PMC9590669
- DOI: 10.1097/ALN.0000000000004241
Hypoxia and Hypercoagulability in COVID-19: Chicken or the Egg?
Conflict of interest statement
Competing Interests
Dr. Fernandez-Bustamante has received funding for research not related with the topic of this article from the United States Department of Defense (Washington, D.C.) and the Merck Sharp & Dohme Corp. (Kenilworth, New Jersey) investigator-initiated studies program. The authors are not supported by, nor maintain any financial interest in, any commercial activity that may be associated with the topic of this article.
Comment on
-
Suppression of Fibrinolysis and Hypercoagulability, Severity of Hypoxemia, and Mortality in COVID-19 Patients: A Retrospective Cohort Study.Anesthesiology. 2022 Jul 1;137(1):67-78. doi: 10.1097/ALN.0000000000004239. Anesthesiology. 2022. PMID: 35412597 Free PMC article.
Similar articles
-
COVID‑19 and ischemic stroke: Mechanisms of hypercoagulability (Review).Int J Mol Med. 2021 Mar;47(3):21. doi: 10.3892/ijmm.2021.4854. Epub 2021 Jan 15. Int J Mol Med. 2021. PMID: 33448315 Free PMC article. Review.
-
Hypercoagulability following COVID-19 infection: at what stage is it safe to do a free flap?Br J Oral Maxillofac Surg. 2020 Dec;58(10):e232-e233. doi: 10.1016/j.bjoms.2020.08.092. Epub 2020 Aug 20. Br J Oral Maxillofac Surg. 2020. PMID: 33008624 Free PMC article. No abstract available.
-
Blood Hyperviscosity: A Novel Link Between Hyperinflammation and Hypercoagulability in COVID-19.J Am Coll Cardiol. 2022 Jul 26;80(4):329-331. doi: 10.1016/j.jacc.2022.04.061. J Am Coll Cardiol. 2022. PMID: 35863849 Free PMC article.
-
COVID-19 and Hypercoagulability: Potential Impact on Management with Oral Contraceptives, Estrogen Therapy and Pregnancy.Endocrinology. 2020 Dec 1;161(12):bqaa121. doi: 10.1210/endocr/bqaa121. Endocrinology. 2020. PMID: 32725207 Free PMC article. No abstract available.
-
Fibrinolysis Shutdown in COVID-19: Clinical Manifestations, Molecular Mechanisms, and Therapeutic Implications.J Am Coll Surg. 2021 Jun;232(6):995-1003. doi: 10.1016/j.jamcollsurg.2021.02.019. Epub 2021 Mar 22. J Am Coll Surg. 2021. PMID: 33766727 Free PMC article. Review.
References
-
- Schultz MJ, Haitsma JJ, Zhang H, Slutsky AS: Pulmonary coagulopathy as a new target in therapeutic studies of acute lung injury or pneumonia: A review. Crit Care Med 2006; 34:871–7 - PubMed
-
- Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, Xiang J, Wang Y, Song B, Gu X, Guan L, Wei Y, Li H, Wu X, Xu J, Tu S, Zhang Y, Chen H, Cao B: Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study. Lancet 2020; 395:1054–62 - PMC - PubMed
-
- Corey KM, Olson LB, Naqvi IA, Morrison SA, Davis C, Nimjee SM, Que LG, Bachelder RE, Kraft BD, Chen L, Nair SK, Levy JH, Sullenger BA: Suppression of fibrinolysis and hypercoagulability, severity of hypoxemia, and mortality in COVID-19 patients: A retrospective cohort study. Anesthesiology 2022; 137:67–78 - PMC - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Medical