Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 May 5;109(5):973.
doi: 10.1016/j.ajhg.2022.03.017.

Response to Mörseburg et al

Affiliations
Comment

Response to Mörseburg et al

Victoria L Wyckelsma et al. Am J Hum Genet. .
No abstract available

PubMed Disclaimer

Comment on

References

    1. Mörseburg A., Pagani L., Malyarchuk B., Derenko M., Kivisild T. Response to Wyckelsma et al.: Loss of a-actinin-3 during human evolution provides superior cold resilience and muscle heat generation. Am. J. Hum. Genet. 2022;108 doi: 10.1016/j.ajhg.2022.03.014. - DOI - PMC - PubMed
    1. Wyckelsma V.L., Venckunas T., Houweling P.J., Schlittler M., Lauschke V.M., Tiong C.F., Wood H.D., Ivarsson N., Paulauskas H., Eimantas N., et al. Loss of alpha-actinin-3 during human evolution provides superior cold resilience and muscle heat generation. Am. J. Hum. Genet. 2021;108:446–457. doi: 10.1016/j.ajhg.2021.01.013. - DOI - PMC - PubMed
    1. MacArthur D.G., Seto J.T., Raftery J.M., Quinlan K.G., Huttley G.A., Hook J.W., Lemckert F.A., Kee A.J., Edwards M.R., Berman Y., et al. Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans. Nat. Genet. 2007;39:1261–1265. doi: 10.1038/ng2122. - DOI - PubMed
    1. Friedlander S.M., Herrmann A.L., Lowry D.P., Mepham E.R., Lek M., North K.N., Organ C.L. ACTN3 allele frequency in humans covaries with global latitudinal gradient. PLoS One. 2013;8 doi: 10.1371/journal.pone.0052282. - DOI - PMC - PubMed
    1. Amorim C.E.G., Acuna-Alonzo V., Salzano F.M., Bortolini M.C., Hunemeier T. Differing evolutionary histories of the ACTN3∗R577X polymorphism among the major human geographic groups. PLoS One. 2015;10 doi: 10.1371/journal.pone.0115449. - DOI - PMC - PubMed

LinkOut - more resources