doi: 10.1007/978-1-0716-2273-5_22.
Microarray-Based Screening of Putative HSP90 Inhibitors Predicted and Isolated from Microorganisms
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- PMID: 35524063
- DOI: 10.1007/978-1-0716-2273-5_22
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Microarray-Based Screening of Putative HSP90 Inhibitors Predicted and Isolated from Microorganisms
Methods Mol Biol.
2022.
Abstract
Protein microarrays are useful tools for detecting the presence of a target where different prey and bait combinations exist. Here we describe the extended application for a functional target-oriented screening assay with full length Heat shock proteins (HSPs ) for the identification of novel compounds.
Keywords: ATP-Cy5; Anti HSP90 inhibitor; Heat shock proteins; Natural products; Protein microarray.
© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.
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